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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03416257
Other study ID # 2015-5145
Secondary ID K01HL129892
Status Completed
Phase
First received
Last updated
Start date April 12, 2004
Est. completion date April 4, 2017

Study information

Verified date June 2018
Source Albert Einstein College of Medicine, Inc.
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In the present study, the investigators sought to prospectively examine the associations of plasma levels of TMAO (trimethylamine oxide), choline, betaine, dimethylglycine, and sarcosine with risk of incident carotid artery plaque, assessed by repeated B-mode carotid artery ultrasound imaging over a 7-year period, in women and men with and without HIV infection from the WIHS (Women Interagency HIV Study) and MACS (Multicenter Aids Cohort Study).


Recruitment information / eligibility

Status Completed
Enrollment 737
Est. completion date April 4, 2017
Est. primary completion date September 1, 2013
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- participants who underwent carotid artery imaging for plaque assessment at a baseline visit (2004-2006) and at a follow-up visit (2011-2013).

Exclusion Criteria:

- a history of coronary heart disease, individuals with prevalent diabetes or prevalent carotid artery plaques at baseline

Study Design


Related Conditions & MeSH terms


Intervention

Other:
No intervention


Locations

Country Name City State
n/a

Sponsors (2)

Lead Sponsor Collaborator
Albert Einstein College of Medicine, Inc. National Heart, Lung, and Blood Institute (NHLBI)

Outcome

Type Measure Description Time frame Safety issue
Primary incident carotid artery plaque assessed by repeated B-mode carotid artery ultrasound imaging 2011-2013
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