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TMAO and Atherosclerosis in HIV

Carotid Artery Plaque Clinical Trial

Official title:
Gut Microbial-related Choline Metabolite Trimethylamine-N-oxide is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection

Clinical Trial Summary

In the present study, the investigators sought to prospectively examine the associations of plasma levels of TMAO (trimethylamine oxide), choline, betaine, dimethylglycine, and sarcosine with risk of incident carotid artery plaque, assessed by repeated B-mode carotid artery ultrasound imaging over a 7-year period, in women and men with and without HIV infection from the WIHS (Women Interagency HIV Study) and MACS (Multicenter Aids Cohort Study).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03416257
Study type Observational
Source Albert Einstein College of Medicine, Inc.
Contact
Status Completed
Phase
Start date April 12, 2004
Completion date April 4, 2017
View Details
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