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Clinical Trial Summary

High density lipoprotein cholesterol (HDL-C) is in the centrum of the process of reverse cholesterol transport from peripheral cells to the liver[10]. HDL-C promotes endothelial generation of nitric oxide (NO) and improves endothelial function and arterial vasoreactivity[11]. In several studies, lower HDL-C level was reported to be associated with increased coronary artery disease (CAD) risk[12-14]. HDL-C also has anti- inflammatory and anti-oxidant activities[15,16]. Concerning anti-inflammatory activity, HDL-C inhibits the activation of monocytes/macrophages and neutrophils[17,18] and inhibits the expression of endothelial adhesion molecules, such as vascular cell adhesion molecule-1 (VCAM-1) and E-selectin[15].

In this study we aimed to investigate the relation of HDL-C level with systemic inflammatory markers in patients with cardiac syndrome X (CSX).


Clinical Trial Description

n/a


Study Design

Observational Model: Case-Crossover, Time Perspective: Retrospective


Related Conditions & MeSH terms


NCT number NCT02095964
Study type Observational
Source Bursa Yüksek Ihtisas Education and Research Hospital
Contact
Status Completed
Phase N/A
Start date March 2012
Completion date January 2014

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