Cardiovascular Diseases Clinical Trial
Official title:
Clinical Study of Effects of Sodium Tanshinone IIA Sulfonate on Pulmonary Hypertension
Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA
isolated as the main pharmacologically active natural compound from a traditional Chinese
herbal medicine,the dried root of Salvia miltiorrhiza Bunge known as Danshen. Danshen has
been known for the function of improving body functions such as activating blood circulation
and removing blood stasis according to the theory of traditional Chinese medicine. Danshen
and its various formula products including STS have been long-time widely used in oriental
countries, especially China to treat various inflammatory and cardiovascular diseases for
its pharmacological actions, including vasodilatation, anticoagulation, anti-inflammation,
and free radical scavenging,with negligible adverse effects observed.
The investigator's objective is to evaluate whether STS exhibits beneficial effects on
pulmonary hypertension. This is a randomized, controlled, multicentre clinical trial study.
90 patients with pulmonary hypertension will be enrolled in this study.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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