Cardiovascular Diseases Clinical Trial
Official title:
Acute Myocardial Infarction and Unstable Angina Patients With PCSK9 Inhibitor Usage Study
Acute coronary syndrome (ACS) is a lethal disease, reduced low-density lipoprotein (LDL) cholesterol due to inhibition of proprotein convertase subtilisin/kexin 9 (PCSK9) reduces cardiovascular events and improve cardiovascular prognosis. we assuming that PCSK9 inhibitor could bring metabolic change in serum, in order to investigate the metabolic modification, we conduct this clinical trial.
| Status | Recruiting |
| Enrollment | 100 |
| Est. completion date | April 23, 2023 |
| Est. primary completion date | April 23, 2022 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 75 Years |
| Eligibility | Inclusion Criteria: - New diagnosis ACS patient by serum biomarker and coronary arteriography. Exclusion Criteria: - Severe renal dysfunction acute or chronic bacterial and viral infections sleep apnea cancer |
| Country | Name | City | State |
|---|---|---|---|
| China | Tangzhiming Li | Shenzhen | Guangdong |
| Lead Sponsor | Collaborator |
|---|---|
| Shenzhen People's Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | cardiovascular prognosis | composite outcome of time to first occurrence of cardiovascular death, myocardial infarction, unstable angina and heart failure. | 52 weeks |
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