PPG to Predict Ejection Fraction & Other Echographic Data in the General

Status Completed

Clinical Trial Summary

The investigators are aiming to investigate the association between ejection fraction (EF) determined by echocardiography and signals obtained from Photoplethysmography (PPG) in the general population. The investigators are also aiming to investigate the association between blood pressure and signals obtained from PPG in the general population. Finally, the investigators are also aiming to investigate the association between signals obtained from PPG in the general population to cardioechographic findings such as, valvular heart disease, structural heart diseases, cardiomyopathies, pericardial disease etc.

Clinical Trial Description

The investigators are proposing a cross-sectional cohort study, where any individual, 18 years old or older, scheduled for an echocardiography at Tulane University's outpatient cardiology clinic can be included. After consenting participants, information on their demographics, personal health habits, medications, and medical history will be collected via reviewing, their electronic medical health records. All participants will undergo an echocardiography as part of their routine medical care by their treating physician. Important echocardiographic findings will be noted such as, EF, valvular heart disease, pericardial disease, cardiomyopathies and structural heart disease. Additionally, PPG recordings will be collected simultaneously while performing echography using the Biostrap wristband. The investigators will analyze the association between each echographic imaging feature, and the PPG waveform obtained. PPG waveform features will be used to develop a predictive model capable of calculating an estimate of ventricular ejection fraction without echocardiography. All echocardiograms will be performed by experienced operators at Tulane Medical Center facilities. The study will occur at a single study site Tulane Medical Center and clinics, with appropriate facilities and equipment to conduct the study accurately and safely. An experienced echocardiogram technician or cardiology fellow will collect the PPG recordings using the Biostrap application. De-identified echocardiogram reports, including information on LVEF will be matched with the participant's pulse report. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04843371
Study type	Observational
Source	Tulane University
Contact
Status	Completed
Phase
Start date	August 20, 2021
Completion date	April 20, 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05428787` - Resynchronization in Patients With HF in AF Trial Undergoing Pace & AVNA Strategy With LBBAP Compared With BiV Pacing	N/A
Not yet recruiting	`NCT05567445` - Outcome of Cardiomyopathic Adults Admission in ICU.
Completed	`NCT02555527` - Contrast Echocardiography Cost Effectiveness for Left Ventricular Thrombus Assessment	N/A
Completed	`NCT00371891` - Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS)	Phase 4
Recruiting	`NCT05552521` - Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants
Recruiting	`NCT04166331` - Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion	Phase 3
Terminated	`NCT06331507` - Refinement and Assessment of New MRI Technologies for Cardiovascular Exams Using the Phillips CMR Patch	N/A
Completed	`NCT01953523` - Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions	N/A
Recruiting	`NCT04695119` - Sepsis in the ICU-II
Completed	`NCT03228966` - Ped HIV - Echo Study: Kenya
Not yet recruiting	`NCT06348732` - Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings
Recruiting	`NCT05556369` - Genetic Characterization of Cardiomyopathies (POLICARDIOMIO2021)
Recruiting	`NCT04520646` - A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy	N/A
Not yet recruiting	`NCT03899298` - Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions	Phase 1
Completed	`NCT04323852` - Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?	Phase 4
Completed	`NCT03527381` - Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery	Phase 1/Phase 2
Withdrawn	`NCT02462213` - Prospective Identification of Cardiac Amyloidosis by Cardiac Magnetic Resonance Imaging	N/A
Active, not recruiting	`NCT00418041` - Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)	N/A
Not yet recruiting	`NCT06091475` - Therapy to Maintain Remission in Dilated Cardiomyopathy	N/A
Recruiting	`NCT03317964` - Genetic Basis of Pacing-induced Cardiomyopathy

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

PPG to Predict Ejection Fraction and Other Echographic Data in the General Population

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms