Cancer Clinical Trial
Official title:
US-Doppler and Procoagulant Microparticles for the Diagnosis of Asymptomatic DVT in Advanced Cancer Patients With Poor Performance Status
The aim of this study is to determine the prevalence of asymptomatic lower extremity DVT
detected by US-Doppler and procoagulant microparticles in a selected group of cancer
patients suffering from an advanced stage of the disease.
An attempt will be made to determine whether there is a correlation between this prevalence
and various clinical and laboratory parameters.
The association between malignancy and venous thromboembolism(VTE) is well known. VTE is one
of the most common complications seen in cancer patients Early detection of VTE can identify
patients who may benefit from anticoagulant therapy and prevent morbidity and mortality.
There are recommendations for hospitalized cancer patients who are bedridden with an acute
medical illness to receive prophylaxis, but in practice this is not clear cut.It has been
shown, in other selected groups of patients that Ultrasound Doppler can be used in order to
diagnose asymptomatic DVT (deep vein thrombosis). Hematological coagulation tests, including
procoagulant microparticles will be performed for the evaluation of coagulation profile, in
order to evaluate the possible correlation between the prevalence of asymptomatic DVT and
these laboratory parameters.
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Observational Model: Case-Only, Time Perspective: Prospective
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