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NCT ID: NCT00613652 Completed - Cancer Clinical Trials

A Phase I, Dose-Escalation Study to Assess the Safety and Drug Levels in Blood of AZD4877 in Japanese Adult Patients

Start date: January 2008
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to evaluate the safety and tolerability of AZD4877 on a weekly schedule in Japanese patients with advanced solid malignancies

NCT ID: NCT00612703 Completed - Cancer Clinical Trials

A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors

Start date: February 2008
Phase: Phase 1
Study type: Interventional

To determine the safety, tolerability and recommended Phase 2 dose of ARQ 197 when administered in combination with erlotinib to patients with advanced solid tumors

NCT ID: NCT00610246 Completed - Cancer Clinical Trials

A Study of Radiation With Sorafenib in Advanced Cancer

Start date: May 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the combination of radiation treatment and an anti-angiogenic drug called sorafenib (or BAY 43-9006 or Nexavar) to determine the effects of this combination on cancers but also on side effects of radiation treatment. This study will also determine the highest safe dose of sorafenib that can be given with radiation treatment.

NCT ID: NCT00609921 Completed - Cancer Clinical Trials

A Phase 1 Study of ARQ 197 in Patients With Solid Tumors

Start date: January 2008
Phase: Phase 1
Study type: Interventional

This is a Phase 1, open label, dose escalation study of ARQ 197 in patients with advanced/recurrent solid tumors. The purpose of this study is to determine the safety, tolerability and recommended Phase 2 dose (RP2D) of ARQ 197.

NCT ID: NCT00607529 Completed - Cancer Clinical Trials

Clinical Evaluation of an Investigational Blood Creatinine Point-of-Care Test Device

Start date: August 2007
Phase: N/A
Study type: Observational

This study is being done to see if the Nova Creatinine Meter can give a correct measure of creatinine (a blood test used to measure kidney function) when the blood is taken from a capillary (smallest type of blood vessels). The Nova Creatinine Meter is a hand held device that can be used in a clinic to measure creatinine in about 50 seconds. Current laboratory creatinine testing can take up to an hour. Since chemotherapy patients need to have their creatinine measured prior to treatment, this meter could make testing easier and faster.

NCT ID: NCT00606515 Completed - Cancer Clinical Trials

Pharmacokinetics Study of Liposomal Paclitaxel in Humans

LPS-PK-H
Start date: February 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether there is any difference of the pharmacokinetics of two taxane formulations, paclitaxel injection and liposomal paclitaxel in Chinese cancer patients with solid tumors.

NCT ID: NCT00603551 Completed - Cancer Clinical Trials

Screening of Bone Mineral Density in Women Who Have Received Chemotherapy

Start date: November 2006
Phase:
Study type: Observational

The hypothesis is that postmenopausal women who have received chemotherapy have a greater bone loss than the same age controls. The aim of this study is to obtain baseline bone mineral density (BMD) data on women with breast and gynecological cancers who have received chemotherapy. By comparing the Z scores of postmenopausal women who have received chemotherapy with age matched controls this hypothesis can be evaluated. Another goal of the study is to compare the T-score of a Heel Bone Density Scan to the T-score of the DXA Scan to see if there is a good correlation between peripheral and DXA scores.

NCT ID: NCT00600444 Completed - Cancer Clinical Trials

PORTAS 2, Comparing Venae Sectio Versus Punction of Vena Subclavia for Insertion of a Totally Implantable Access Port

PORTAS2
Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this trial is to investigate if the success rate of punction the vena subclavia (99% in retrospective studies) will be 15% higher than the success rate of venae sectio (80% in retro and prospective studies) for implantation of a totally implantable access ports.

NCT ID: NCT00597519 Completed - Cancer Clinical Trials

A Myeloablative Conditioning Regimen and Total Body Irradiation Followed by the Transplantation for Patients With Hematological Malignancy

Start date: March 2006
Phase: Phase 2
Study type: Interventional

In this study two cord blood collections will be used to increase the number of cord blood cells you will receive on transplant day. We call this a "double unit" cord blood transplant. A previous study suggests double unit cord blood transplant may have a better result. The main purpose of this study is to find out how good a cord blood transplant using two cord blood collections from two different babies is at curing you of your cancer. Double unit cord blood transplants are now being studied as a way to increase the number of cord blood cells given to bigger children and adult patients. Based on studies that have already been done double unit cord blood transplant appears to be safer than if only one cord blood unit is used. However, double unit cord blood transplant is a fairly new form of treatment.

NCT ID: NCT00595777 Completed - Cancer Clinical Trials

Edinburgh Pain Assessment Tool (EPAT©) Study

EPAT©
Start date: December 2007
Phase: N/A
Study type: Interventional

To determine if the institutionalisation of a regular systematic approach to the assessment of pain in inpatient cancer units using the Edinburgh Pain Assessment Tool (EPAT©) leads to better control of pain than that achieved by usual care.