Clinical Trials Logo

Filter by:
NCT ID: NCT00002193 Completed - HIV Infections Clinical Trials

Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if it is safe and effective to add a new protease inhibitor (PI), 141W94, to an anti-HIV regimen that includes 2 nucleoside reverse transcriptase inhibitors (NRTIs).

NCT ID: NCT00002194 Completed - HIV Infections Clinical Trials

An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.

Start date: n/a
Phase: Phase 1
Study type: Interventional

To evaluate the potential pharmacokinetic interaction between nevirapine and clarithromycin, and to determine the effects of nevirapine on cytochrome P450 3A4 (CYP3A4) activity in vivo.

NCT ID: NCT00002195 Completed - HIV Infections Clinical Trials

A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if it is safe and effective to add 141W94 to an anti-HIV regimen that includes retrovir plus epivir.

NCT ID: NCT00002196 Completed - HIV Infections Clinical Trials

A Study of CI-1012 in HIV-Infected Patients

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to see if it is safe and effective to give CI-1012 to HIV-infected patients who do not have any symptoms of the disease. This study also examines how the body handles CI-1012.

NCT ID: NCT00002197 Completed - HIV Infections Clinical Trials

A Study of 1592U89 in HIV-Infected Children

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to see if it is safe to give 1592U89 to children (aged 6 months until 14th birthday) with advanced HIV infection who have few treatment options available. The study also examines the effect 1592U89 has on the levels of HIV in the blood.

NCT ID: NCT00002198 Completed - HIV Infections Clinical Trials

A Study of 1592U89 and Ethanol When Given Together to HIV-Infected Patients

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to see how the body processes 1592U89 and ethanol (pure grain alcohol) when they are given together.

NCT ID: NCT00002199 Completed - HIV Infections Clinical Trials

A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.

Start date: n/a
Phase: Phase 3
Study type: Interventional

To compare the safety, tolerance, early antiviral activity, and durability of antiviral response of the lamivudine (3TC)/zidovudine (ZDV)/1592U89 arm versus the 3TC/ZDV/indinavir (IDV) arm. To determine the effect of the two arms on clinical efficacy as determined by the occurrence of new CDC, defined class B/C events, survival, medical resource utilization, and the development of plasma viral genotypic and phenotypic resistance.

NCT ID: NCT00002200 Completed - HIV Infections Clinical Trials

A Study of 1592U89 in HIV-Infected Adults

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to see if it is safe and effective to give 1592U89 to HIV-positive adults. This study also examines the influence previous anti-HIV treatment has on the effectiveness of 1592U89.

NCT ID: NCT00002201 Completed - HIV Infections Clinical Trials

A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected Patients

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to see if it is safe and effective to give ritonavir plus nelfinavir to HIV-infected patients. This study will also see how ritonavir and nelfinavir are absorbed by the body and how they affect the level of HIV in the blood.

NCT ID: NCT00002202 Completed - HIV Infections Clinical Trials

A Comparison of 141W94 and Indinavir in HIV-Infected Patients

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if 141W94 is as safe and effective as indinavir when used with nucleoside reverse transcriptase inhibitors (NRTIs) for 48 weeks. This study also examines what effect other drugs have on how the body handles 141W94.