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NCT ID: NCT03499691 Completed - Clinical trials for End Stage Renal Disease

Exploratory Study to Explore the Safety and Efficacy of the HDx Therapy Using Theranova 500 Dialyzer in Comparison to Hemodiafiltration

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

Today it is well established that middle molecules comprise several compounds that are not effectively removed by high-flux dialyzers, and effective clearance of large middle molecules in the process of dialysis depends on the dialyzer membrane having large enough pore sizes, larger than the conventional high-flux dialyzers. Studies have found associations between levels of large middle molecule uremic toxins and immune dysfunction and inflammation, as well as adverse outcomes. This indicates that dialysis membranes having larger pores, enabling an expanded HD (HDx) with more effective removal of large middle molecules, can have a positive impact on the inflammatory state. While data is starting to appear on the long-term use of the HDx therapy, little is still known on how large middle molecules and inflammation markers are affected over time.

NCT ID: NCT03507634 Completed - Postoperative Pain Clinical Trials

Opioid Free Anesthesia in Bariatric Surgery

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

This study compares the intraoperative opioid free anesthesia approach in laparoscopic bariatric surgery to a conventional opioid- based anesthesia. Half of participants will receive opioid free anesthesia with dexmedetomidine, lidocaine and ketamine while the other half will receive opioid based anesthesia with fentanyl, remi-fentanyl and ketamine

NCT ID: NCT03509220 Completed - Clinical trials for Gastrointestinal Disease

Safety and Efficacy of PBK-1701TC for Bowel Cleansing Before Colonoscopy

Start date: April 11, 2018
Phase: Phase 3
Study type: Interventional

This study evaluates the efficacy, safety and tolerability of PBK-1701TC for bowel cleansing before colonoscopy. Half the participants will receive PBK-1701TC and while the other will receive standard oral preparation.

NCT ID: NCT03519438 Completed - Breast Cancer Clinical Trials

Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis

Start date: April 11, 2018
Phase:
Study type: Observational

The aim of this study is to examine alterations in the skin microbiome that occur during radiation therapy. The study design will examine changes secondary to ionizing radiation, and correlate these changes with the development and severity of radiation dermatitis. The goal is to improve understanding of the mechanism of radiation dermatitis.

NCT ID: NCT03522675 Completed - Allergy Clinical Trials

NeoMatriX Wound Matrix Collagen Dressing Skin Prick Test

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the potential of NeoMatriXTM Wound Matrix to cause an allergic response to healthy volunteers using a skin prick test.

NCT ID: NCT03533387 Completed - Healthy Volunteers Clinical Trials

Study of MN-166 (Ibudilast) Extended Release Tablet Formulations Compared With Capsules in Healthy Volunteers

Start date: April 11, 2018
Phase: Phase 1
Study type: Interventional

To compare the bioavailability and pharmacokinetic profiles of two different formulations MN-166 50mg, extended release (ER) tablets with MN-166 10mg capsules in a single-dose regimen in healthy volunteers

NCT ID: NCT03534206 Completed - Clinical trials for Renal Cell Carcinoma

Using Virtual Reality (VR) Models for Preoperative Planning - University of Tennessee

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

A prospective, randomized, controlled study designed to assess whether digital virtual reality (VR) models, created from existing CT scans and MRIs, provide surgeons with an improved understanding of their patients' anatomy, resulting in more efficient operations (robotic partial nephrectomy) and improved patient care

NCT ID: NCT03541694 Completed - Yellow Fever Clinical Trials

Passive Enhanced Safety Surveillance of Stamaril® Vaccine in Korea

Start date: April 11, 2018
Phase:
Study type: Observational

This is a passive enhance safety surveillance (ESS) of Stamaril® vaccine in Korea. The objective is to collect suspected related adverse events following vaccination with Stamaril® in routine practice.

NCT ID: NCT03551821 Completed - Alopecia Areata Clinical Trials

Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata

Start date: April 11, 2018
Phase: Phase 2
Study type: Interventional

The main objective of this study is to assess the safety, tolerability and efficacy of ATI-50002 Topical Solution in subjects with unilateral or bilateral loss of eyebrow hair due to alopecia areata (AA), alopecia universalis (AU) or alopecia totalis (AT).

NCT ID: NCT03559218 Completed - Clinical trials for Radiation Dermatitis

KeraStat(R) Cream for Radiation Dermatitis

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

The primary objectives of the proposed research are to evaluate patient use of KeraStat Cream and collect data to inform a larger future trial.