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NCT ID: NCT05957562 Completed - Leak, Anastomotic Clinical Trials

Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair

EArAzygousvp
Start date: April 10, 2020
Phase: N/A
Study type: Interventional

Azygos vein preservation revisited: impact on early outcomes after repair of Esophageal atresia/ Tracheo-Esophageal Fistula in newborns. A randomized controlled study.

NCT ID: NCT04367103 Completed - Hypotension Clinical Trials

Norepinephrine for Hypotension in Cesarean Section

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

Hypotension is a very common consequence of the sympathetic vasomotor block caused by spinal anesthesia for cesarean section. Maternal symptoms such as nausea, vomiting and dyspnea frequently accompany severe hypotension, and adverse effects on the fetus, including depressed APGAR scores and umbilical acidosis, have been correlated with severity and duration of hypotension. Because hypotension is frequent, vasopressors should be used routinely and preferably prophylactically.

NCT ID: NCT04604665 Completed - Critical Illness Clinical Trials

Evaluation of Two Levels of Frequency of Repositioning in the Reduction of Pressure Ulcers

PENFUP-2
Start date: April 10, 2021
Phase: N/A
Study type: Interventional

PENFUP FASE 2, It is a multicenter study by parallel conglomerates, planned in order to evaluate the efficacy between two levels of frequency of postural change in intensive care units for adults of hospitals in various regions of Colombia.

NCT ID: NCT04771481 Completed - Effect of Drug Clinical Trials

Metoclopramide for Acute Upper GI Bleeding

Start date: April 10, 2021
Phase: Phase 4
Study type: Interventional

The presence of blood clot in stomach limited quality of endoscopic view ,which affect successful rate of hemostatic endoscopy in patient with acute upper gastrointestinal bleeding. The study is aimed to evaluate the efficacy of metoclopramide, as pro-kinetic agent ,for gastric visualization in the patient with acute UGIB; double-blind randomized controlled trial and two centers study. The patient were randomly assigned to receive either metoclopramide (10mg) intravenously or placebo before endoscopy 30-120 min. The primary endpoint was endoscopic yield, assessed by objective gastric visualized scoring systems. Secondary end points include duration of endoscope, technical success rate, the need for second-look EGD, units of blood transfusion, length of hospital stay and 30-day rebleeding rate.

NCT ID: NCT04781842 Completed - Parkinson Disease Clinical Trials

Effect of a Boxing Program on People With Parkinson Disease

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

This study is investigating the impact of a boxing training program on people with Parkinson Disease. The investigators were provided data for the intervention group retrospectively by the organizers of the boxing club to assess participants' benefit from participation. The outcome measures were selected to measure different aspects of functional mobility. Of particular interest is the impact of challenging whole-body activities designed for boxing and their impact on turning speed and gait. The second phase of the study will gather control group information from people with Parkinson Disease who have not participated in a boxing program to compare differences in pre-test and post-test data over a period of 12 weeks. The specific population and study design are currently pending global pandemic restrictions. Subject recruitment will involve people who have never had access to a program of this nature. An alternative population for recruitment may involve the same participants from the boxing club in a crossover study format since the boxing club has been suspended for over a year due to health and safety concerns during the pandemic. The control group of either situation would be instructed to carry on with their daily activities as usual without changing their physical activity. We hypothesize that the intervention group would show greater improvements in functional mobility compared to the control group.

NCT ID: NCT04783766 Completed - Clinical trials for Healthy Adult Subjects

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Start date: April 10, 2021
Phase: Phase 1
Study type: Interventional

The purposes of this study are to: 1. Learn about the safety of CK-3773274 after a single dose and multiple doses in Chinese healthy adult subjects. 2. Learn how healthy subjects tolerate CK-3773274 after a single dose and multiple doses. 3. Find out how much CK-3773274 is in the blood after a single dose and multiple doses. 4. Determine the effect of doses of CK-3773274 on the pumping function of the heart. 5. Evaluate the effect CYP2D6 genetic polymorphisms on how the body metabolizes CK-3773274.

NCT ID: NCT04796051 Completed - Neck Pain Clinical Trials

Comparison Between Effect of Posterior Cervical Weighting and Deep Cervical Flexion Exercise on Forward Head Posture

FHP
Start date: April 10, 2021
Phase: N/A
Study type: Interventional

It has been reported that the head protrudes forward relative to the body from the sagittal plane associated with the anterior shifting of the line of gravity (LOG) relative to the base of support (BOS). On the other hand, the center of gravity (COG) has changed with the forward head posture (FHP) and is related to mechanical and musculoskeletal modifications due to postural control, which affects the whole body balance. Griegel-Morris et al. Reported that, after evaluating eighty-eight healthy participants, 66% had a forward head posture (FHP). In addition, he stated that the inverted head posture in the forward head posture will not only cause neck problems, but also can extend to the shoulder joint and thoracic spine. As a result, it causes a general imbalance in the musculoskeletal system. Jung-Ho Kang and his colleagues examined the effect of daily sitting times of computer users on dynamic and static balance and stated that balance ability decreased in heavy computer users. Another study on forward head posture (IBP) revealed that it limits ankle joint movement, especially in ankle plantarflexion.

NCT ID: NCT04821999 Completed - SARS-CoV Infection Clinical Trials

Diode Laser 940 nm in Management of Loss of Taste Sensation

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

The global pandemic has recently emerged by transmission of SARS-CoV2 virus. The virus has had a massive impact on health, wealth and social aspects worldwide. Since the identification of this virus in Wuhan, China, millions of cases has been diagnosed worldwide with mortality rates ranging from 3% to 12 %

NCT ID: NCT04824820 Completed - Clinical trials for Urinary Incontinence

Improving Female Sexual Wellness

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effect of commercially available genital vibrator use on sexual health, female pelvic floor disorders, and overall quality of life among a diverse population of women.

NCT ID: NCT04835337 Completed - Clinical trials for Protective Effect of Air Purifier on Children's Health

The Health Benefits of Indoor Air Filtration Among Children

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

This study aims to explore the health benefits of air purifier on the impact of air pollutants on children's health.