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NCT ID: NCT05952817 Not yet recruiting - Blood Disease Clinical Trials

Physiotherapy for Children With Sickle Cell Disease: A Randomized Controlled Trial

RCT
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Primary aim to determine the effects of immersive VR on pain management in children with SCD. Secondary aim to determine the effects of immersive VR in musculoskeletal dysfunction in children with SCD and health-related quality of life.

NCT ID: NCT05953623 Not yet recruiting - Clinical trials for Stroke, Acute Ischemic

Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients

Start date: August 1, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety and feasibility of intra-arterial albumin infusion for patients with acute ischemic stroke after successful thrombectomy and to further explore the optimal dose of albumin through the implementation of a 3 + 3 dose-escalation design.

NCT ID: NCT05953649 Not yet recruiting - Clinical trials for Mechanical Ventilation

Effect of Early Extracorporeal Diaphragm Pacing Combined With Tilt Table in Ventilated Patients.

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to test the effect of 1week of extracorporeal diaphragm pacing (EDP) combined either with or without tilt table verticalization (TTV) on diaphragm function in patients with mechanical ventilation compared to conventional physiotherapy (CPT).

NCT ID: NCT05954130 Not yet recruiting - Sexual Health Clinical Trials

The Effect of Sexual Health-Specific Mobile Application Support on Sexual Life in Pregnancy

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Pregnancy is an important process with many changes in a woman's life. During this period, the sexual lives of couples may be affected due to anatomical, physiological and psychological changes. While sexual intercourse during pregnancy strengthens the harmony between spouses, emotional bond, and self-confidence of the woman, its role is important in terms of the continuation of the marriage. The development of technology in the world and in our country has led to an increase in the use of mobile devices. The emergence of telehealth and mobile applications with the Covid-19 pandemic has enabled individuals to access information whenever they want and more easily. The aim of this study was to determine the effect of mobile application support given to pregnant women for sexual health on sexual function and quality of sexual life. It is planned to develop a mobile application in this direction by preparing a guide, with the foresight that sexuality during pregnancy is not an easily expressed subject and that pregnant women and health workers need training materials. After the power analysis, it is aimed to reach a total of 70 people, 35 in the experimental group and 35 in the control group. Data will be collected with Personal Information Form, Female Sexual Function Index, Sexual Life Quality Scale and Qualitative Interview Form. Based on the developed guide and mobile application, training will be given to pregnant women in the first, second and third trimesters, and it is thought that the mobile application support specific to sexual health during pregnancy may contribute to increasing sexual function and sexual life quality.

NCT ID: NCT05954247 Not yet recruiting - Healthy Volunteers Clinical Trials

Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 in Healthy Adult Volunteers

Start date: August 1, 2023
Phase: Phase 1
Study type: Interventional

This study aims to evaluate the safety and pharmacokinetic characteristics after administration of DWJ1543 in healty adult volunteers.

NCT ID: NCT05954338 Not yet recruiting - Healthy Volunteers Clinical Trials

Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 With DWC202307 in Healthy Adult Volunteers

Start date: August 1, 2023
Phase: Phase 1
Study type: Interventional

This study aims to evaluate the safety and the pharmacokinetics of DWJ1543 with concomitant multiple oral doses of DWC202307 in healthy adult volunteers.

NCT ID: NCT05954884 Not yet recruiting - Hypertension Clinical Trials

Community-based HEARTS Intervention (Pilot)

CB-HEARTS
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to assess the feasibility of health system change intervention with a focus on recruitment of patients with hypertension, initiation of antihypertensive medication, and retention of patients in care at the Community Clinics (CC) with a goal of finalizing the key features of a team- and community-based intervention in rural Bangladesh. Patients with uncomplicated hypertension will be enrolled, their medical treatment will be provided from CC by a Community Health Care Provider (CHCP) according to the telemedicine-based instruction of Medical Officer from Upazila Health Complex (UHC) with provision of referral to UHC for an in-person evaluation. Participants will be followed up periodically and their medicine will be refilled accordingly.

NCT ID: NCT05955209 Not yet recruiting - Clinical trials for Metastatic Castration-resistant Prostate Cancer

Clinical Study on the Efficacy and Safety of RC48-ADC in the Treatment of Metastatic Castration Resistant Prostate Cancer (mCRPC)

Start date: August 1, 2023
Phase: Phase 2
Study type: Interventional

This is a single-arm, open, single-center clinical study to evaluate the efficacy and safety of RC48-ADC in patients with mCRPC who have progressed after NHT. A total of 40 patients with mCRPC with immunohistochemically confirmed HER2 expression who had progressed after treatment with at least one novel endocrine therapy will be included in this study.

NCT ID: NCT05956431 Not yet recruiting - Heart Arrest Clinical Trials

RCT Study of Levosimendan Improving Prognosis of Cardiac Arrest

Start date: August 1, 2023
Phase: Phase 4
Study type: Interventional

This study is intended to use a multicenter, double-blind, superior effect, placebo controlled randomized controlled clinical trial to explore the therapeutic effect of Levosimendan (within 6 hours after the recovery of spontaneous circulation) on mortality and multiple organ dysfunction such as heart and brain in patients with cardiac arrest who have recovered from active Cardiopulmonary resuscitation but have low cardiac output syndrome and coma, and the impact of 30-day mortality and neurological function after cardiac arrest.

NCT ID: NCT05958355 Not yet recruiting - Parkinson Disease Clinical Trials

Effects of Functional Postural Control Training on Functional Performance in People With Parkinson's Disease With Freezing of Gait

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this single-blinded, randomized controlled study aims to establish the effects of functional postural control training on functional performance and FOG in PD individuals with FoG as compared with treadmill training.