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NCT ID: NCT05382117 Enrolling by invitation - Clinical trials for Neurumusculoskeletal Disorders

Cardiac Rhythm and Affecting Factors in Patients Hospitalized in the Physical Therapy and Rehabilitation Clinic

Start date: December 29, 2021
Phase:
Study type: Observational [Patient Registry]

In our study, it is aimed to evaluate the cardiac rhythms of patients who are decided to receive inpatient treatment in the physical therapy and rehabilitation clinic due to any neuromusculoskeletal diseases with 24 hour rhythm holter follow up on the day of hospitalization and three weeks after hospitalization and to determine the factors that may affect this result if a significant change is observed between the two measurements.The present results will guide the determination of the exercise duration, intensity, type and severity of the exercises to be created within the scope of the treatment programs of the patients and will lead to similar studies.

NCT ID: NCT05263765 Enrolling by invitation - Aortic Occlusion Clinical Trials

Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery

Start date: December 29, 2022
Phase:
Study type: Observational

Aortic occlusion (AO) for trauma has traditionally been accomplished by supra-diaphragmatic clamping of the descending thoracic aorta via emergent thoracotomy or as an initial step during laparotomy.

NCT ID: NCT05619783 Enrolling by invitation - Clinical trials for Amyotrophic Lateral Sclerosis

Extension Study Evaluating The Safety And Tolerability of AMX0035

Start date: December 29, 2022
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the safety and tolerability of AMX0035 over 108 weeks of open label treatment for participants previously enrolled in Study A35-004 (PHOENIX).

NCT ID: NCT03772535 Enrolling by invitation - Clinical trials for Arthroplasty Complications

Pharmacogenetics for Pain Management in Joint Replacement Patients

PGx
Start date: December 3, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the ability to use pharmacogenetic testing in a joint replacement practice to prescribe the most effective pain medicine for a specific patient.

NCT ID: NCT03918590 Enrolling by invitation - Clinical trials for Diabetic Macular Edema

Post Intravitreal Injection Topical NSAID vs. Patching

Start date: December 3, 2018
Phase: Phase 4
Study type: Interventional

A prospective randomized trial, to evaluate post-injection comfort measures comparing topical NSAID (nepafenac 0.3% suspension) and patching.

NCT ID: NCT04039815 Enrolling by invitation - Sepsis, Severe Clinical Trials

Vitamin C, Vitamin B1 and Steroid in Sepsis

Start date: December 3, 2019
Phase: Phase 4
Study type: Interventional

A randomized controlled trial to test the synergic modulation effect of vitamin C, thiamine and hydrocortisone in patients with severe sepsis or septic shock.

NCT ID: NCT04132271 Enrolling by invitation - Clinical trials for Oropharyngeal Dysphagia

Swallowing and Nutritional Treatment on OD Patients

OD
Start date: December 3, 2019
Phase: N/A
Study type: Interventional

Dysphagia is a difficulty during the swallowing process (transportation food from the mouth to the stomach. Oropharyngeal Dysphagia (OD) is diagnosed by videofluoroscopy and faringolaringoscopy. OD threatens the efficacy and safety of swallowing, contributing to an increased risk of aspiration and pneumonia. There are different interventions aimed to change and improve the physiology of swallowing; however, OD can be an important predictor of the progression of malnutrition in different types of patients. Malnutrition is defined as an acute or chronic disease whereby an energy imbalance, lack of energy, protein or other nutrients causes measurable and adverse effects on body composition, functional and clinical outcomes. In addition, it leads to a decrease in the quality of life. Objective: To establish a strategy of nutritional treatment and swallowing rehabilitation in patients with dysphagia. Hypothesis: An adequate nutritional intervention in content and consistency, combined with swallowing rehabilitation in patients with dysphagia, will improve the nutritional status and clinical evolution of patients with dysphagia.

NCT ID: NCT04209296 Enrolling by invitation - Clinical trials for Major Depressive Disorder

Chart Review of Patients Undergoing Ketamine Infusions

Start date: December 3, 2019
Phase:
Study type: Observational

The Canadian Rapid Treatment Center of Excellence (CRTCE) is a healthcare facility principally focused on providing best practices of intravenous ketamine treatment to adult patients suffering from mental health conditions. The center focuses specifically on treating individuals suffering from major depression disorder, bipolar disorder, post-traumatic stress disorder and obsessive compulsive disorder as their primary diagnosis. Herein, this retrospective analysis aims to look at past data in order to further develop our understanding of ketamine in the use of psychiatry.

NCT ID: NCT04798430 Enrolling by invitation - Clinical trials for Familial Hypercholesterolemia

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction

LIBerate-OLE
Start date: December 3, 2020
Phase: Phase 3
Study type: Interventional

The study is to assess the long-term safety, tolerability, and efficacy after 48 and 72 weeks with monthly (Q4W [<31 days]) dosing of subcutaneous (SC) LIB003 300 mg administered in patients with CVD or at high risk for CVD (including HoFH and HeFH) on stable diet and oral LDL-C lowering drug therapy who completed one of the LIB003 Phase 3 base studies.

NCT ID: NCT05055388 Enrolling by invitation - Clinical trials for Intensive Care Units

Epidemiological Investigation of Sepsis in Obstetrics Admitted to ICU

Start date: December 3, 2020
Phase:
Study type: Observational

Sepsis is still the main cause of maternal death, accounting for 11% of maternal deaths. Early identification of high risk factors of sepsis and early intervention can improve the prognosis of pregnant women with sepsis. At present, there is no epidemiological investigation report on sepsis in ICU in China.