Breast Cancer Clinical Trial
Official title:
Adapted Physical Activity Effect on Aerobic Function and Fatigue in Patients With Breast Cancer Treated in Adjuvant Phase
Physical exercise has been identified as a major item of many chronic diseases and cancer
rehabilitation.
Therefore, physical activity for health is a valid and relevant way to improve quality of
life and to manage cancer patient fatigue. The aim of the study is the assessment of the
effects of a physical activity retraining program on aerobic capacity, strength and fatigue,
in a breast cancer population treated by adjuvant chemotherapy.
Physical exercise has been identified as a major item of many chronic diseases and cancer
rehabilitation. It contributes to an improvement in the quality of life and to a decrease in
the current treatment side effects and mortality. Cancer in association with treatment
toxicity and an inactive lifestyle lead to a fall in physical capability and causes problems
in daily activities. The physical capacity and the tolerance for exercise fall simultaneously
leading to a deconditioning vicious circle which increases physical, psychological and
emotional symptoms of fatigue. Therefore, physical activity for health is a valid and
relevant way to improve quality of life and to manage cancer patient fatigue. The aim of the
study is the assessment of the effects of a physical activity retraining program on aerobic
capacity, strength and fatigue, in a breast cancer population treated by adjuvant
chemotherapy.
A total of 44 subjects is required. The programme is organised as follows: Arm A (aerobic and
strength training) and during the 27 weeks of treatment (chemotherapy and radiotherapy); Arm
B (control group). This study includes 3 assessments phases (T0: before adjuvant
chemotherapy; T1 (week 27) and T2: final evaluation at the 54th week). These assessments
include: cardiopulmonary exercise test including maximal oxygen uptake test (VO2max),
six-minute walk test, muscular testing, assessment of physical activity (IPAQ questionnaire),
fatigue (MFI20 questionnaire), quality of life (EORTC QLQ C30), anxiety and depression
symptoms (HADS) and nutritional evaluation: BMI and total body photonic absorption.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04681911 -
Inetetamab Combined With Pyrotinib and Chemotherapy in the Treatment of HER2 Positive Metastatic Breast Cancer
|
Phase 2 | |
Terminated |
NCT04066790 -
Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer
|
Phase 2 | |
Completed |
NCT04890327 -
Web-based Family History Tool
|
N/A | |
Completed |
NCT03591848 -
Pilot Study of a Web-based Decision Aid for Young Women With Breast Cancer, During the Proposal for Preservation of Fertility
|
N/A | |
Recruiting |
NCT03954197 -
Evaluation of Priming Before in Vitro Maturation for Fertility Preservation in Breast Cancer Patients
|
N/A | |
Terminated |
NCT02202746 -
A Study to Assess the Safety and Efficacy of the VEGFR-FGFR-PDGFR Inhibitor, Lucitanib, Given to Patients With Metastatic Breast Cancer
|
Phase 2 | |
Active, not recruiting |
NCT01472094 -
The Hurria Older PatiEnts (HOPE) With Breast Cancer Study
|
||
Completed |
NCT06049446 -
Combining CEM and Magnetic Seed Localization of Non-Palpable Breast Tumors
|
||
Withdrawn |
NCT06057636 -
Hypnosis for Pain in Black Women With Advanced Breast Cancer: A Feasibility Study
|
N/A | |
Recruiting |
NCT05560334 -
A Single-Arm, Open, Exploratory Clinical Study of Pemigatinib in the Treatment of HER2-negative Advanced Breast Cancer Patients With FGFR Alterations
|
Phase 2 | |
Active, not recruiting |
NCT05501769 -
ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer
|
Phase 1 | |
Recruiting |
NCT04631835 -
Phase I Study of the HS-10352 in Patients With Advanced Breast Cancer
|
Phase 1 | |
Completed |
NCT04307407 -
Exercise in Breast Cancer Survivors
|
N/A | |
Recruiting |
NCT03544762 -
Correlation of 16α-[18F]Fluoro-17β-estradiol PET Imaging With ESR1 Mutation
|
Phase 3 | |
Terminated |
NCT02482389 -
Study of Preoperative Boost Radiotherapy
|
N/A | |
Enrolling by invitation |
NCT00068003 -
Harvesting Cells for Experimental Cancer Treatments
|
||
Completed |
NCT00226967 -
Stress, Diurnal Cortisol, and Breast Cancer Survival
|
||
Recruiting |
NCT06019325 -
Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
|
N/A | |
Recruiting |
NCT06006390 -
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
|
Phase 1/Phase 2 | |
Recruiting |
NCT06037954 -
A Study of Mental Health Care in People With Cancer
|
N/A |