Breast Cancer Clinical Trial
Official title:
Deep Inspiration Breath-hold Radiotherapy for Left-sided Breast Cancer in Reducing Early Cardiac Injury: a Phase II Prospective Study
Postoperative breast radiotherapy (RT) has been associated with increased risk of heart toxicity. However, there is a lack of knowledge for radiation-induced early cardiovascular injury, especially for hypofractionated RT. This study aims to prospectively detect and predict early clinical or subclinical cardiac events in women undergoing adjuvant RT for breast cancer.
| Status | Recruiting |
| Enrollment | 166 |
| Est. completion date | June 30, 2023 |
| Est. primary completion date | June 30, 2022 |
| Accepts healthy volunteers | |
| Gender | Female |
| Age group | 18 Years to 70 Years |
| Eligibility | Inclusion Criteria: - Primary left-sided breast cancer post surgery - Planning for adjuvant breast/chest wall +-RNI Exclusion Criteria: - History of cardiovascular disease - Previous chest radiation - Bilateral breast cancers |
| Country | Name | City | State |
|---|---|---|---|
| China | Cancer Hospital, Chinese Academy of Medical Sciences | Beijing |
| Lead Sponsor | Collaborator |
|---|---|
| Shu lian Wang |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Incidence of clinical or subclinical cardiac injury | predefined cardiac events | two years |
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