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Body Weight clinical trials

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NCT ID: NCT05362175 Completed - Birth Weight Clinical Trials

Cross Sectional Area of Umbilical Cord Versus Hadlock's Formula in Prediction of Neonatal Birth Weight

Start date: July 15, 2021
Phase:
Study type: Observational

Ultrasound measurement of cross sectional area of umbilical cord might offer advantage over Hadlock's formula for accurate estimation of actual birth weight at term gestation leading to prevention of large number of maternal and neonatal morbidity and mortality.

NCT ID: NCT05351866 Terminated - Depression Clinical Trials

Digital Therapeutic for Adolescent Depressive Symptoms in Hematology, Oncology, and Weight Management

Start date: January 26, 2023
Phase: N/A
Study type: Interventional

The primary aims of the proposed research are to assess the feasibility, acceptability, and preliminary evidence of efficacy of a self-guided, cognitive behavioral therapy (CBT)-based mobile app intervention (SparkRx) for the treatment of adolescents presenting with symptoms of depression in specialty medical care settings (e.g.Hematology/Oncology, Weight Management, etc.) at Children's Health System of Texas (CHST).

NCT ID: NCT05350111 Recruiting - Body Weight Changes Clinical Trials

CArdioMetabolic Prevention in Adolescents

CAMP
Start date: March 27, 2022
Phase: N/A
Study type: Interventional

The aim of the CArdioMetabolic Prevention (CAMP) pilot study is to investigate the effect of a group intervention on lifestyle in adolescents and on at least one adult family member. This will be followed by telemedicine tools for 12-week-time period. A face-to-face group intervention addressing nutrition, physical activity and well being together with an assessment of anthropometry parameters, body composition, questionnaires, blood and stool sampling will be done before and after 12 weeks of telemedicine. The study aims to investigate: - the effect of 12-week intervention on body weight, anthropometry parameters and cardiometabolic markers in comparison to the conventionally led obesity clinic for adolescents - the compliance with telemedicine tools that will focus on the support of balance nutrition, physical activity (evaluation of daily steps through smart bands) and family well being in regards to the effect on anthropometry and laboratory parameters - the effect of the intervention on data from questionnaires (eating disorders, quality of life, psychological health) before and after the intervention - data analysis of family members with respect to theirs offspring

NCT ID: NCT05328791 Recruiting - Obesity Clinical Trials

Effectiveness of a Mindfulness Based Diet Program on Weight Loss

Start date: May 15, 2022
Phase: N/A
Study type: Interventional

Meditation interventions, including mindfulness-based approaches, can be effective in reducing psychological stress . Mindfulness meditation, which cultivates awareness of present-moment experience with a nonjudging attitude, is theorized to promote adaptive self-regulation,which is thought to be key to maintaining long-term eating habits and appetite regulation.In the light of this information, in this study, it is aimed to observe the effect of mindfulness approach on body weight and appetite control.

NCT ID: NCT05314374 Enrolling by invitation - Healthy Clinical Trials

Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype

Start date: May 12, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this research is to study the effect of the study drug (a conjugated bile acid dietary supplement) or placebo on cell function, hormones and body weight.

NCT ID: NCT05311462 Recruiting - Obesity Clinical Trials

An Observational Cohort Study to Obese Patients With Weight Cycling

Start date: April 8, 2022
Phase:
Study type: Observational

Medical nutritional weight loss was effective in reducing body weight and waist circumference and improving a range of cardiovascular disease risk factors in obese patients, with an average effective weight loss of 11.1 kg (about 13%) over 4 months in obese adults. However, it was found through the follow-up visit that these subjects had lost only 5.8kg from baseline and regained about half of their weight (5.1 kg, 48%) after 21 months of weight-loss intervention. In this study, intestinal flora analysis was proposed to identify the causes of individual repeated weight loss failure, structure changes of weight cycling and the advantage species of flora, and explore different intestinal microbiota(microbial genomics) in ending weight loss, obesity-related genetic characteristics (SNPs loci and RNA seq), metabolite(metabolomics)and potential interaction between appetite-related hormones and weight cycling triggers. This study aimed to provide new insights for implementing personalized weight loss programs to improve the success rate of weight loss. The obese patients who failed to lose weight repeatedly were recruited from Peking Union Medical College Hospital. Research Contents:(1) Comparison of anthropometric, biochemical, energy consumption, and intestinal microbiota related indicators between groups; (2) Genotyping to screen out differential SNPs loci;(3) Analysis of the interaction between genes and environmental factors in different metabolic types of obesity. (4) A group of healthy volunteers with normal weight as the healthy control group.

NCT ID: NCT05307523 Completed - Down Syndrome Clinical Trials

Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

To explore the effects of Partial Body Weight Support (PBWS) within an enriched play environment for infants with Down Syndrome (DS), who are not yet walking, to better understand how PWBS may impact their mobility; exploration; and overall activity level. - Hypothesis1 A: Infants will demonstrate increased movement counts on an ActiGraph during intervention compared to a control phase. Hypothesis 1B: Infants will demonstrate a higher frequency of exploratory behaviors during the intervention as compared to a control phase. - Hypothesis 2: Infants will demonstrate an increased rate of improvement in Gross Motor Function Measure scores after the intervention compared to a control phase. - Hypothesis 3: Infants will demonstrate higher parent-reported mastery motivation on the Dimensions of Mastery Questionnaire after the intervention compared to a control phase.

NCT ID: NCT05305313 Recruiting - Anesthesia Clinical Trials

Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System

Start date: April 19, 2022
Phase: Phase 4
Study type: Interventional

The pharmacokinetic profile of various drugs is altered in obese patients especially those administered by the intravenous route. Propofol is the commonly used intravenous anesthetic agent for induction and maintenance of anaesthesia as part of total intravenous anaesthesia (TIVA) regimen. A major concern with propofol dosing based on total body weight (TBW) in obese patients is disproportionate drug administration leading to undue drug accumulation in body with a potential to overdosing, delayed recovery from anaesthesia, and adverse hemodynamic outcome. Studies on propofol dosing based on various weight scalars have recommended that lean body weight (LBW) should be used for calculating bolus dose during anaesthesia induction and TBW or adjusted body weight (ABW) for arriving at an infusion dose required for maintenance of anesthesia. Although propofol delivery based on dose calculated by TBW has been well researched the evidence for propofol delivery based on dose calculated by ABW is lacking. Recent advance in the delivery of propofol has been the development of computer controlled anaesthesia delivery systems. These devices deliver propofol based on patient's frontal cortex electrical activity as determined by bispectral index (BIS). Evaluation of anaesthesia delivery by these systems has shown that they deliver propofol and maintain depth of anaesthesia with far more precision as compared to manual administration. One such indigenously developed computer controlled anaesthesia delivery system is the closed loop anesthesia delivery system (CLADS). CLADS functions on control of processed EEG response parameter captured from anesthetized patients with the help of a BIS- monitor, which is continuously fed into an automated drug infusion pump. The infusion pump then accordingly delivers the anesthetic drug to the patients based on pharmacodynamic requirements. The investigators plan to evaluate the propofol maintenance dose requirement based on TBW versus ABW using CLADS for propofol delivery.

NCT ID: NCT05295836 Completed - Clinical trials for Antioxidative Stress

Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes

Start date: February 10, 2022
Phase: N/A
Study type: Interventional

This clinical study evaluates the acute effect of glycerol ingestion on performance (power output), weight, urine specific gravity, biochemical (antioxidants and lactate) and metabolic (indirect calorimetry) markers in international athletes in hot conditions. The investigators hypothesized that acute glycerol ingestion can prevent performance loss (power generated at submaximal intensity) in hot conditions. To justify this hypothesis, the investigators will measure the aforementioned markers, which could establish a cause-effect relationship between acute glycerol intake and decreased performance loss in hot conditions.

NCT ID: NCT05285150 Completed - Balance Clinical Trials

The Weighting of the Balance

Start date: December 1, 2022
Phase:
Study type: Observational

Summary Introduction: Falls are involuntary events that cause loss of balance and hit the body on the ground or on another firm surface that stops it. 40% of people with various neurological disorders fall one or more times, and of all these, 21% suffer a fall-related injury. Objective and instrumented gait analysis is an important tool for estimating the risk of falls in patients. Objective: To describe the protocols used by physical therapist residing in Argentina when categorizing a balance problem within the framework of neurorehabilitation, vestibular rehabilitation, geriatrics and gerontology. Identify the barriers and facilitators self-perceived by physical therapist that make it difficult to weight deficiencies in balance. Method: An observational, descriptive, cross-sectional study of the online survey type will be carried out. The recommendations given by the Checklist for Reporting of Survey Studies will be used. The survey, which was created by the researchers of this study, will consist of 26 items divided into 4 sections. It will be aimed at all those physical therapist in Argentina who are dedicated to neurorehabilitation, vestibular rehabilitation, geriatrics and gerontology. The type of sampling used will be non-probabilistic by snowball, which will be done online through the SurveyMonkeyTM tool.