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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT01976130
Other study ID # IIBSP-MUC-2009-20
Secondary ID
Status Active, not recruiting
Phase N/A
First received October 22, 2013
Last updated September 7, 2016
Start date June 2012
Est. completion date June 2018

Study information

Verified date September 2016
Source Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Contact n/a
Is FDA regulated No
Health authority Spain: Ethics Committee
Study type Interventional

Clinical Trial Summary

Study hypothesis:

Chronic Obstructive Pulmonary Disease (COPD) patients with chronic bacterial colonization have lower levels of mucins and antimicrobial peptides in their airways


Description:

Main objective:

(1) To investigate the expression of mucins and antimicrobial peptides in patients with severe COPD and their relationship with the presence of bacteria in the airway


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 45
Est. completion date June 2018
Est. primary completion date March 2018
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- COPD

Exclusion Criteria:

- Acute exacerbation in the last 4 weeks

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science


Related Conditions & MeSH terms


Intervention

Procedure:
Bronchoscopy


Locations

Country Name City State
Spain Hospital de la Santa Creu i Sant Pau Barcelona

Sponsors (3)

Lead Sponsor Collaborator
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Instituto de Salud Carlos III, Sociedad Española de Neumología y Cirugía Torácica

Country where clinical trial is conducted

Spain, 

Outcome

Type Measure Description Time frame Safety issue
Primary Mucins in sputum Day 1 No
Secondary Antimicrobial peptides in sputum Day 1 No