Bacterial Infection in COPD Clinical Trial
Official title:
Mechanisms of Lung Defense and Their Relationship With Airway Infection in Chronic Obstructive Pulmonary Disease (COPD)
Study hypothesis:
Chronic Obstructive Pulmonary Disease (COPD) patients with chronic bacterial colonization
have lower levels of mucins and antimicrobial peptides in their airways
Status | Active, not recruiting |
Enrollment | 45 |
Est. completion date | June 2018 |
Est. primary completion date | March 2018 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - COPD Exclusion Criteria: - Acute exacerbation in the last 4 weeks |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
Country | Name | City | State |
---|---|---|---|
Spain | Hospital de la Santa Creu i Sant Pau | Barcelona |
Lead Sponsor | Collaborator |
---|---|
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Instituto de Salud Carlos III, Sociedad Española de Neumología y Cirugía Torácica |
Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mucins in sputum | Day 1 | No | |
Secondary | Antimicrobial peptides in sputum | Day 1 | No |