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Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study — LE-Heart  

Atherosclerosis Clinical Trial

Official title:
Observational Study for Identification of Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study (LE-Heart)

Clinical Trial Summary

Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions. The aim of the study is to identify novel genetic- and biological-markers of atherosclerosis. Atherosclerosis is assessed in the coronary arteries using coronary angiography as well as in the carotid artery (intima-media-thickness) and peripheral vessels (ankle brachial index). Association analysis of genetic and metabolic markers with atherosclerotic burden will be performed to identify novel factors of disposition to atherosclerotic vascular disease.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00497887
Study type Observational
Source University of Leipzig
Contact Joachim Thiery, MD PhD
Phone +49-341-9722201
Email thiery@medizin.uni-leipzig.de
Status Recruiting
Phase N/A
Start date December 2006
View Details
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