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Arterial Hypertension clinical trials

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NCT ID: NCT04023565 Recruiting - Metabolic Syndrome Clinical Trials

Moxonidine + Perindopril in Hypertensive Patients With Metabolic Syndrome

COMPOSER
Start date: March 11, 2019
Phase: Phase 4
Study type: Interventional

The aim of study is to assess the angioprotective effects of antihypertensive combination therapy with perindopril 10 mg and moxonidine 0.4-0.6 mg in patients with arterial hypertension, metabolic syndrome, and obesity, who had Pulse Wave Velocity (PWV) > 10 m/s on the previously administered two-component combination antihypertensive therapy. Open-label non-comparative prospective study for 24 week for each patient.

NCT ID: NCT03982758 Recruiting - Clinical trials for Arterial Hypertension

Acute Effect of Isometric Exercise on Blood Pressure in Hypertensive Patients

Start date: December 9, 2019
Phase: N/A
Study type: Interventional

International recommendations advocate dynamic or isometric strength training as an adjunct to aerobic exercise. Due to a lack of consensus, this research addresses the acute effects of isometric exercises by handgrip or lower limb isometry as a hypotensive strategy in hypertensive adults.

NCT ID: NCT03917758 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors

GliRACo1
Start date: October 10, 2018
Phase: N/A
Study type: Interventional

Subjects treated with Canagliflozin, Dapagliflozin and Empagliflozin obtained improvement on blood pressure values, body weight and cardiovascular mortality but pathophysiological explanations of these effects are not yet known.

NCT ID: NCT02676414 Recruiting - Clinical trials for Arterial Hypertension

Validation of a Hypertension Education Program

Start date: August 2015
Phase: N/A
Study type: Interventional

The primary purpose of this study is to assess the effect of participating in the interactive hypertension education program of the German Hypertension League (DHL©) "My blood pressure - OK!" on office systolic blood pressure.

NCT ID: NCT02346695 Recruiting - Clinical trials for Arterial Hypertension

Association Between Left Ventricular Deformation and Aerobic Exercise Capacity in Untreated Arterial Hypertension

Start date: June 2012
Phase: N/A
Study type: Observational

Impaired myocardial deformation may determine cardiac diastolic dysfunction. The investigators will investigate the vascular determinants of myocardial deformation and twisting-untwisting and their interrelation with exercise capacity in patients with untreated arterial hypertension

NCT ID: NCT02002585 Recruiting - Clinical trials for Arterial Hypertension

Renal Protection Using Sympathetic Denervation in Patients With Chronic Kidney Disease

KPS
Start date: November 2013
Phase: Phase 2
Study type: Interventional

Kidney protection study (KPS 1) is a prospective randomized clinical study comparing the use of renal denervation (RDN) and optimal medical therapy in subjects with chronic kidney disease stage 3-4 and resistant arterial hypertension to optimal medical therapy alone. Renal denervation is a modern endovascular method used to treat resistant hypertension. The method is being extended to other groups of patients, where the sympathetic tone is increased beyond resistant hypertension. Because of the character of the disease, we hypothesize that renal denervation can reduce or prevent progressive deterioration of kidney functions in this patient population. The aim of this clinical study is to show that renal denervation has protective effects on the progression of chronic renal insufficiency.

NCT ID: NCT01959997 Recruiting - Atrial Fibrillation Clinical Trials

Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI

Start date: September 2013
Phase: Phase 2
Study type: Interventional

The objective of this study is to compare the elimination of atrial fibrillation in patients with recurrent atrial fibrillation despite prior pulmonary vein isolation (PVI) when undergoing repeat PVI (control) vs repeat PVI plus renal denervation.

NCT ID: NCT01901549 Recruiting - Clinical trials for Acute Coronary Syndrome

Renal Denervation in Patients After Acute Coronary Syndrome

ACSRD
Start date: June 2013
Phase: Phase 2
Study type: Interventional

This study is aimed to evaluate the effect of renal denervation to decreasing blood pressure and left ventricle remodeling progression in patients after acute coronary syndrome.

NCT ID: NCT01191450 Recruiting - Clinical trials for Arterial Hypertension

Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial Hypertension

CARD
Start date: August 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Chlorthalidone 25 mg + amiloride hydrochloride 5 mg association in the treatment of elderly patients with arterial hypertension.

NCT ID: NCT01132001 Recruiting - Clinical trials for Arterial Hypertension

Ambulatory Versus Home Blood Pressure Measurement

Start date: October 2009
Phase: N/A
Study type: Observational

This is a prospective study comparing the three blood pressure monitoring methods on the diagnosis of arterial hypertension. Blood pressure of each subject will be evaluated with clinic, home and 24h ambulatory blood pressure measurements in three visits