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Aneurysm clinical trials

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NCT ID: NCT00591968 Completed - Clinical trials for Abdominal Aortic Aneurysm

Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community

Start date: January 2008
Phase: N/A
Study type: Interventional

The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard of patient care throughout the world. Perhaps the safest and most cost effective mode of teleradiology today is telesonography. The current project attempts to determine the extent that telesonography improves the standard of care within a rural government-run primary clinic within the Dominican Republic. The work reported herein is intended to compare the use of telesonography to the current standard of sonographic examination (referral to government hospital 60km from target clinic). The study was conducted by randomly assigning 100 patients with clinical indications for sonographic examination into experimental and control groups. Following a 60-day implementation period, the following research questions will be addressed: 1) To what extent does the use of asynchronous telesonography increase the percentage of definitive diagnoses based on the total number of scans (definitive diagnoses / total number of scans)? 2) To what extent does the use of asynchronous telesonography increase the continuity of care for patients? 3) To what extent does the elapsed time between scanning and final radiological interpretation decrease with the use of asynchronous telesonography? This study will also look at the history of telemedicine / telesonography and its dissemination into the mainstream practice of medicine, explore training protocols that may be used to assist others to establish new telesonography programs in a developing nations, and discuss both advances and persistent barriers to the implementation of telesonography programs. Hypothesis: The use of a store-and-forward telesonography system in this setting will increase the speed and number of final diagnoses per scan received by the target clinic and will increase the continuity of care by increasing the number and speed of follow-up appointments to the target clinic.

NCT ID: NCT00590759 Completed - Clinical trials for Aortic Aneurysm, Thoracic

Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms

Start date: August 2005
Phase: N/A
Study type: Interventional

The purpose of this post-approval study is to evaluate the long-term performance of the GORE TAG® Thoracic Endoprosthesis (TAG device) in the primary treatment of descending thoracic aortic (DTA) aneurysms

NCT ID: NCT00583414 Completed - Clinical trials for Abdominal Aortic Aneurysm

Endovascular Exclusion of Abdominal Aortic Aneurysms in High Risk Patients

Start date: September 1998
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the role of abdominal aneurysm and iliac aneurysm exclusion using an endovascular prosthesis.

NCT ID: NCT00583050 Completed - Clinical trials for Abdominal Aortic Aneurysm

Endovascular Exclusion of TAAA/AAA Utilizing Fenestrated/Branched Stent Grafts

Start date: February 2001
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the role of fenestrated/branched stent-grafts in the exclusion of abdominal aortic and thoracoabdominal aneurysms.

NCT ID: NCT00577616 Completed - Clinical trials for Ruptured Aorta-iliac Aneurysms

Ruptured Aorta-iliac Aneurysms: Endo vs. Surgery

ECAR
Start date: December 2007
Phase: N/A
Study type: Interventional

The aim of this multicenter randomized trial is to compare the endovascular repair versus conventional repair for ruptured aorta-iliac aneurysms observed on CT scan in stable patients with suitable anatomy. The main awaited result is the significant reduction of the mortality of the conventional repair.

NCT ID: NCT00562289 Completed - Ischemic Stroke Clinical Trials

Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence

CLOSE
Start date: December 2007
Phase: Phase 3
Study type: Interventional

A patent foramen ovale (PFO) is found more frequently in patients with an ischemic stroke than in control subjects. Therapeutic options to prevent stroke recurrence include antiplatelet drugs, oral anticoagulants, and transcatheter closure of the foramen. However, there are no published studies showing convincingly the superiority of any one of these strategies in preventing stroke recurrence. The aim of this randomized clinical trial is to assess whether chronic anticoagulation on the one hand and transcatheter on the other hand are superior to chronic antiplatelet therapy in preventing stroke recurrence.

NCT ID: NCT00556309 Completed - Cerebral Aneurysm Clinical Trials

Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing.

OCT
Start date: January 2007
Phase:
Study type: Observational

The purpose of this study is to identify the healing of aneurysms in three month use Optical Coherence Tomography image to measure outcomes in post coiled aneurysms. Endovascular therapeutic coiling is a widely used procedure in the management of aneurysms, which is an angiogram .

NCT ID: NCT00543270 Completed - Clinical trials for Abdominal Aortic Aneurysm

Powerlink Bifurcated Stent Graft Long-Term Follow-up Study

Start date: October 2005
Phase: N/A
Study type: Interventional

Endologix Infrarenal Bifurcated Stent Graft Study

NCT ID: NCT00538967 Completed - Clinical trials for Aortic Aneurysm, Abdominal

The Effect of Doxycycline on Matrix Metalloproteinase Expression and Activity in the Abdominal Aneurysm

Start date: May 2002
Phase: Phase 2
Study type: Interventional

The matrix metalloproteinase-9 (MMP-9) is considered to play a central role in abdominal aortic aneurysm (AAA) initiation. Doxycycline has direct MMP-9 inhibiting properties in vitro, and it effectively suppresses AAA development in rodents. Observed inhibition of AAA progression, and contradictory findings in human studies evaluating the effect of doxycycline therapy on aortic wall MMP-9 suggest that the effects of doxycycline extend beyond MMP-9 inhibition, and that the effect may be dose dependent.

NCT ID: NCT00538421 Completed - Surgery Clinical Trials

Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery

ABSENT
Start date: March 2008
Phase: Phase 4
Study type: Interventional

Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.