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Anemia, Iron Deficiency clinical trials

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NCT ID: NCT04594070 Terminated - Pregnancy Related Clinical Trials

Daily Versus Alternate Day Iron Supplementation for the Treatment of Iron Deficiency Anemia in Pregnancy

Start date: October 27, 2020
Phase: Phase 4
Study type: Interventional

The target population for our study is pregnant women in the first or second trimester with a diagnosis of iron deficiency anemia. If a subject is eligible, written consent will be obtained by person to person contact. Eligible participants will be randomized to receive either daily oral iron supplementation or every other day oral iron supplementation.

NCT ID: NCT03991000 Terminated - Clinical trials for Cardiovascular Diseases

Iron in Patients With Cardiovascular Disease

iCHF-2
Start date: February 28, 2019
Phase: Phase 3
Study type: Interventional

It is now recognized that iron deficiency in cardiovascular disease contributes to impaired clinical outcome.

NCT ID: NCT03933813 Terminated - Anemia Clinical Trials

Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients

Start date: July 29, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study tests the hypothesis that IV iron sucrose infusions given to iron deficient ovarian cancer patients prior to debulking surgery can improve pre-operative iron stores and decrease transfusion of packed red blood cells in the peri-operative period. 21 participants at least 18 years of age with epithelial ovarian cancer of any stage requiring neoadjuvant chemotherapy and surgery will be enrolled. Participants will be on study for a period of up to 3 months.

NCT ID: NCT03774615 Terminated - Clinical trials for Anemia, Iron Deficiency

ORal IrON Supplementation With Ferric Maltol in Patients With Heart Failure Carrying Left Ventricular Assist Devices

ORION-LVAD-1
Start date: March 18, 2019
Phase: Phase 4
Study type: Interventional

This is a open-label, uncontrolled, monocenter, phase IV study. The aim of this study is to detect AEs or SAEs with a relative frequency of at least 11.5% in LVAD patients with iron deficiency anemia treated with oral ferric maltol for 12 weeks.

NCT ID: NCT03610230 Terminated - Clinical trials for Iron Deficiency Anemia Treatment

Iron Isomaltoside Compared With Iron Sucrosein Peritoneal Dialysis Patients

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

1. To compare patient-reported satisfaction, efficacy and short-term safety profile of Monofer® in a single bolus dose with Venofer® in split doses in the treatment of absolute or functional iron deficiency anemia in patients on PD. 2. To compare patient symptomatology on fatigue after treatment of Monofer® compared with Venofer® .

NCT ID: NCT03528564 Terminated - Knee Arthropathy Clinical Trials

Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia

HOPE-Hb
Start date: July 1, 2019
Phase: Phase 2
Study type: Interventional

The HOPE-Hb trial is a phase II study to determine the feasibility and impact of a combination treatment (intravenous iron plus erythropoietin) versus intravenous iron treatment alone on preoperative hemoglobin concentration before hip or knee arthroplasty.

NCT ID: NCT03523455 Terminated - Iron-deficiency Clinical Trials

Iron Aid IPS on Performance, Fatigue and Iron Levels During 12 Weeks of Supplementation and Aerobic Training

Start date: November 29, 2016
Phase: N/A
Study type: Interventional

Participants are required to undergo a screening and qualification before beginning the study. Once qualified, baseline testing is completed in the laboratory. This testing includes: body composition measurements, a blood draw, questionnaires, a VO2 max test, and a time to exhaustion trial. This testing is repeated during week 4 and week 12. At week 8, subjects complete a blood draw and questionnaires only. During the 12 week period, participants will follow an endurance exercise program in which they will train 4 days per week. This is a double-blind study in which participants are randomized into either the placebo or supplement group. They are instructed to ingest the supplement once a day at breakfast. Diet logs are also monitored throughout the duration of the study with the restriction of no red meat.

NCT ID: NCT03485053 Terminated - Clinical trials for Iron Deficiency Anemia

A Single Ascending Study of IOP Injection in Patients With Iron Deficient Anemia

Start date: November 29, 2018
Phase: Phase 2
Study type: Interventional

The purpose is to evaluate the efficacy and safety of IOP Injection (MPB-1514) for the treatment of iron-deficient anemia (IDA).

NCT ID: NCT03371173 Terminated - Clinical trials for Hypertension, Pulmonary

ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1)

ORION-PH-1
Start date: March 27, 2018
Phase: Phase 3
Study type: Interventional

This is an explorative, open-label, uncontrolled, single center study to explore the preliminary safety, tolerability and efficacy of oral ferric maltol in treating iron deficiency in patients with pulmonary hypertension and iron deficiency anemia.

NCT ID: NCT03218384 Terminated - Iron-deficiency Clinical Trials

Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency

Start date: September 7, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to better understand how body levels of iron affect the ability to exercise in patients with heart failure (HF). Heart failure is a condition in which abnormal pumping action of the heart reduces the flow of blood to the body. Patients with heart failure may feel shortness of breath or leg fatigue when they exercise. Iron is an essential nutrient in the diet. In heart failure patients, low body levels of iron might increase shortness of breath and fatigue.