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Adherence, Medication clinical trials

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NCT ID: NCT06348069 Recruiting - HIV Prevention Clinical Trials

Pharmacy-based PrEP for Young Women Who Sell Sex in Zimbabwe

TOPAZ
Start date: March 25, 2024
Phase: N/A
Study type: Interventional

Pharmacy-based PrEP for Young Women who Sell Sex in Zimbabwe is a cluster-randomized control trial and pilot study co-led by Dr. Euphemia Sibanda, Reader (Associate Professor) of Global Health and Epidemiology at Liverpool School of Tropical Medicine, UK and Research Director at the Centre for Sexual Health and HIV Research (CeSHHAR Zimbabwe) and Dr. Sandra McCoy, Professor of Epidemiology and Biostatistics at the University of California, Berkeley. The goal of the proposed study is to optimize, refine and pilot a pharmacy-based PrEP intervention for female sex workers (FSW) in Zimbabwe. Despite efforts to reach the most impacted and vulnerable populations with PrEP, retention rates, particularly among FSW in Africa, are very low. Relatively high levels of uptake indicate that FSW are interested in PrEP and ready to initiate it, but in most cases fewer than 50% of those who initiate return for medication refills by month 4. Pharmacy-based PrEP has the potential to address known barriers to PrEP retention among FSW such as stigma and access, and coupled with a small escalating incentive in the form of a gift card incentive, could also boost motivation for effective use of PrEP.

NCT ID: NCT06233123 Not yet recruiting - Bronchial Asthma Clinical Trials

Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

asthma adherence is mandatory for disease control

NCT ID: NCT06200623 Not yet recruiting - Bronchial Asthma Clinical Trials

Cognitive and Emotional Factors Relation to Treatment Adherence in Asthmatic Patients in Upper Egypt

Start date: January 1, 2024
Phase:
Study type: Observational

Non-adherence to controller therapy is one of the main reasons of poor asthma control. Adherence to medication in different studies range between 30 and 70% . Several factors related to the disease, to the patient, treatment or physician- patient relationship

NCT ID: NCT06183723 Enrolling by invitation - HIV Infections Clinical Trials

Optimizing Care for Challenging People Living With HIV

Start date: March 18, 2024
Phase: N/A
Study type: Interventional

Conduct an intervention combining social and behavioral health models with digital health technologies to improve their adherence to their medication schedules. The success of the intervention is assessed by comparing adherence rates before and after its implementation to see if there's a notable enhancement in how well patients follow their antiretroviral therapy.

NCT ID: NCT06182280 Not yet recruiting - HIV Infections Clinical Trials

Transmaculine One-on-One and Group Empowerment for Targeted HIV Reduction

TOGETHR
Start date: January 2024
Phase: N/A
Study type: Interventional

Transgender masculine and gender diverse people who have sex with men (TMSM) have an increased risk of HIV and face unique barriers engaging in prevention services. Digitally delivered support interventions addressing HIV prevention barriers delivered by peers in one-on-one or small-group settings may be effective at increasing PrEP engagement. This study examines the independent and combined effects of individual and group-based peer-support interventions on PrEP outcomes. Participants will be randomly assigned to receive: (i) standard-of-care HIV prevention information, (ii) a one-on-one healthy lifestyle intervention tailored for transgender masculine people, (iii) a peer-group based healthy lifestyle intervention for transgender masculine people, or (iv) both the one-on-one and group-based interventions delivered together. The hypotheses are that the individual group-based interventions will result in higher PrEP uptake and persistence than the standard of care and that the combined interventions will be more effective than receiving one individual intervention.

NCT ID: NCT06068309 Recruiting - Hypertension Clinical Trials

Efficacy of CareAide® App in Improving Adherence in Adults With Chronic Diseases

CAREAide
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to study the impact of a medication adherence app, CareAide, in adult population diagnosed with chronic diseases in Malaysian population. The main question[s] it aims to answer are: 1. Can CareAide make people take their medications better and improve their health? 2. Can CareAide improve the health of people with chronic diseases? 3. Does using CareAide make people's lives better? 4. Can CareAide save money when managing chronic diseases? 5. How do people feel about using CareAide? Researchers will ask the participants to use the CareAide app for 6 months and compare the group that used the app with the other group which just received the usual treatment. Researchers will check if they do better with their medications, feel healthier, have a better life, and spend less money. They will check this twice, once after 3 months and again after 6 months. adherence, clinical outcomes, quality of life and economic associated with the app with two follow ups at 3 month intervals.

NCT ID: NCT06059235 Recruiting - Clinical trials for Adherence, Medication

Concordance : a New Concept for Clinical Pharmacy in Partnership With Patients at a Geriatric Day Clinic

COPAPI-G
Start date: January 9, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the impact of pharmaceutical consultations in older patients having a comprehensive geriatric assessment at geriatric day-clinic. The main question it aims to answer is: What is the impact on patient adherence Participants will benefit from medication history taking, medication review, therapeutic education, shared decision-making and follow-up phone call. Researchers will compare with a control group, benefiting from medication history taking and usual care from the geriatric day-clinic.

NCT ID: NCT06056037 Not yet recruiting - Hiv Clinical Trials

Making ART Work Among Brazilian Youth

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

This study seeks to develop and pilot test a theory-based, integrated technology and counseling intervention to improve ART adherence among sexual and gender minority (SGM) young people living with HIV (ages 18-24) in Rio de Janeiro, Brazil. The intervention aims to improve social support, self-efficacy for taking ART, and teach skills for problem-solving barriers to promote better adherence.

NCT ID: NCT05998876 Not yet recruiting - Opioid Use Disorder Clinical Trials

Assessing Dose Taken in Opioid Use Disordered Patients With an Electrochemical Sensor

Start date: February 2024
Phase:
Study type: Observational

CARI Health aims to develop a methadone dose taken sensor that provides real-time data on interstitial fluid (ISF) levels that could be used as a methadone adherence monitor for daily doses. Use of such a monitor would allow for the physician, counselor, patient, and family member to remotely verify that a physician prescribed dose has been taken. Such a verification system can allow methadone clinics greater flexibility in the provision of take-home doses and thus retain more patients in the clinic.

NCT ID: NCT05997914 Not yet recruiting - Stroke Clinical Trials

Storytelling for Reducing Gap in Anticoagulation Use in African Americans With Atrial Fibrillation

Start date: May 2024
Phase: N/A
Study type: Interventional

The overall goal of this study is to evaluate the effectiveness of a previously developed storytelling intervention on anticoagulation (AC) initiation/persistence in African American and Black patients with atrial fibrillation/flutter. The investigators hope to gain knowledge that may help treat atrial fibrillation or flutter and lower stroke and adverse cardiovascular event risks for African American and Black patients by increasing the use of blood thinning medications known as anticoagulants.