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Acute Pain clinical trials

View clinical trials related to Acute Pain.

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NCT ID: NCT05781685 Completed - Acute Pain Clinical Trials

The Influence of Testosterone on Experimental Pain Perception

Start date: October 1, 2017
Phase: Early Phase 1
Study type: Interventional

This trial examined how the administration of exogenous testosterone would influence pain tolerance and other endogenous steroids (i.e. estradiol and progesterone).

NCT ID: NCT05781230 Completed - Knee Osteoarthritis Clinical Trials

The Effect of Exercises of Different Intensity Applied After Total Knee Arthroplasty on Exercise-Induced Hypoalgesia

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to investigate whether exercise-induced hypoalgesia (EIH) is present following exercise in patient after total knee arthroplasty (TKA) and if so, if it changes with exercise intensity. A repeated measures and single-blinded randomized study were done. Thirty-eight patients 24 hours after TKA were randomly assigned to either low intensity exercises (LIE) group or high intensity exercises (HIE) group. An exercise programs lasted for five days during the hospitalization period. Pain severity was assessed by Visual Analog Scale (VAS) (0-10 mm). Pressure pain thresholds (PPTs) were measured over quadriceps and biceps brachii and muscles immediately before and after exercise.

NCT ID: NCT05764616 Completed - Surgery Clinical Trials

Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy

PARARECTUS
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to examine the effect of ultrasound guided bilateral Parasternal Nerve Block combined with rectus sheath block on preoperative analgesia, opioid consumption and respiratory function in patients undergoing cardiac surgery via sternotomy. Half of participants will receive General Anesthesia combined with bilateral parasternal block and rectus sheath block while the other half receive General Anesthesia combined with bilateral parasternal block and infiltration of drainage exits sites with local anesthetic (without performing rectus sheath block)

NCT ID: NCT05764525 Completed - Pain, Postoperative Clinical Trials

Phase 3 Efficacy and Safety of VVZ-149 Injections for Postoperative Pain Following Laparoscopic Colectomy

Start date: July 19, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this phase 3 study is to evaluate the efficacy and safety of VVZ-149 Injections for the treatment of postoperative pain following laparoscopic colectomy.

NCT ID: NCT05752734 Completed - Anesthesia Clinical Trials

Preoperative Dexamethasone to Improve Quality of Recovery After Laparoscopic Bariatric Surgery

Start date: February 2, 2023
Phase:
Study type: Observational [Patient Registry]

In the obese patient, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay. Increasing patient comfort and recovery quality can be achieved by avoiding undesirable effects such as nausea and vomiting, as well as analgesia. In our study, our aim is to evaluate the effect of dexamethasone added to multimodal analgesia on postoperative patient comfort in the obese patient group with a 40-item scale.

NCT ID: NCT05679453 Completed - Pain, Acute Clinical Trials

Lornoxicam Versus Etodolac After Third Molar Surgery

Start date: July 20, 2022
Phase: Phase 4
Study type: Interventional

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

NCT ID: NCT05675358 Completed - Pain, Acute Clinical Trials

Virtual Reality on Pain, Fear, and Emotional Appearance During Phlebotomy in Pediatric Hematology and Oncology Patients

VR-PHO
Start date: March 3, 2022
Phase: N/A
Study type: Interventional

In this study, the effect of virtual reality, which is one of the pain relief methods, on the pain, fear and emotional appearance associated with the procedure, was evaluated in children aged 4-12 years who will undergo phelobotomy in a Pediatric Hematology and Oncology outpatient clinic.

NCT ID: NCT05672394 Completed - Lung Cancer Clinical Trials

US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Thoracic surgeries is known to be one of the most painful surgeries . Multiple analgesic techniques have been used for post operative analgesia including Thoracic epidural , Patient Controlled Analgesia and systemic opioids. Opioids are associated with multiple sied effects including : PONV , Respiratory depression and ileus while thoracic epidural has its own complications such as hemodynamic instability , injury of spinal cord, pneumothorax and epidural hematoma. Peripheral nerve blocks provide good alternative for perioperative analgesia. The purpose of our study is to compare the effectiveness of perioperative continuous serratus anterior plane block versus continuous thoracic epidural in pain management during thoracic surgeries for malignancy resection.

NCT ID: NCT05669924 Completed - Pain Clinical Trials

Neural Correlates of Acute Pain Dynamics

Start date: September 19, 2022
Phase: Phase 2
Study type: Interventional

This work aims to study the neural correlates and determinants of pain dynamics related to changes in a noxious stimulus.

NCT ID: NCT05661734 Completed - Pain Clinical Trials

A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain

Start date: January 9, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of VX-548 in treating acute pain.