β Blocker Use and Mortality in Hospital Survivors of Acute Myocardial Infarction Without Heart Failure

Acute Myocardial Infarction Clinical Trial

Official title:

β Blocker Use and Mortality in Hospital Survivors of Acute Myocardial Infarction Without Heart Failure

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02786654
• Other study ID #: PG/13/81/30474BB
• Status: Completed
• Start date: January 2007
• Est. completion date: June 2013

Study information

• Verified date: June 2019
• Source: University of Leeds
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of the study is to investigate the association between the use of β blockers and mortality among hospital survivors of acute myocardial infarction without heart failure.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 179810
• Est. completion date: June 2013
• Est. primary completion date: June 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• acute myocardial infarction patients only

• aged 18 to 100 years

Exclusion Criteria:

• other final diagnosis besides acute myocardial infarction

• died in-hospital

• patients with missing mortality data

• aged > 100

• patients with previous acute myocardial infarction or angina

• patients who have received coronary interventions before

• patients with heart failure

• patients with ß blocker prior use

• patients contraindicated for ß blocker use

• patients with use of a loop diuretic

Related Conditions & MeSH terms

• Acute Myocardial Infarction
• Heart Failure
• Infarction
• Myocardial Infarction

Locations

Country	Name	City	State
United Kingdom	University of Leeds	Leeds

Sponsors (1)

Lead Sponsor	Collaborator
University of Leeds

Country where clinical trial is conducted

United Kingdom, 

References & Publications (1)

Dondo TB, Hall M, West RM, Jernberg T, Lindahl B, Bueno H, Danchin N, Deanfield JE, Hemingway H, Fox KAA, Timmis AD, Gale CP. ß-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction. J Am Coll Cardiol. 2017 Jun 6;69(22):2710-2720. doi: 10.1016/j.jacc.2017.03.578. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	All cause mortality		1 year
Secondary	All cause mortality		6 months
Secondary	All cause mortality		30 days