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Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of Human Urinary Kallidinogenase combined with endovascular therapy in acute ischemic stroke (AIS) patients with large vessel occlusion.


Clinical Trial Description

A prospective, randomized, double-blind, placebo-controlled, multi-center study of Human Urinary Kallidinogenase or Placebo, combined with endovascular therapy for AIS patients with large vessel occlusion. Approximately 120 eligible subjects will be randomized (1:1) to receive one of the following treatments for 10 days: - Human Urinary Kallidinogenase combined with endovascular therapy (non-bridged) - Placebo combined with endovascular therapy (non-bridged) Primary efficacy of Human Urinary Kallidinogenase will be evaluated at 90 days. The safety of Human Urinary Kallidinogenase will be evaluated through 90 days. End of study evaluation will occur at day 90 or premature discontinuation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06211712
Study type Interventional
Source Huashan Hospital
Contact Qiang Dong, M.D.
Phone 13701747065
Email 13701747065@163.com
Status Not yet recruiting
Phase N/A
Start date April 2024
Completion date December 2025

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