Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

Women With Breast Cancer Clinical Trial

Official title:

To Develop and Implement a Method for Medical Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04588935
• Other study ID #: 20192755
• Status: Completed
• Phase: Phase 2
• Start date: July 1, 2019
• Est. completion date: February 7, 2023

Study information

• Verified date: February 2023
• Source: State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Description:

Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: February 7, 2023
• Est. primary completion date: February 7, 2023
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy.

Exclusion Criteria:

• presence of other oncological diseases

Related Conditions & MeSH terms

• Breast Neoplasms
• Cardiovascular Diseases
• Women With Breast Cancer

Intervention

Drug:
• Bisoprolol; Perindopril;
based on the results of the patient study, different drug therapy regimens for cardiovascular complications during chemotherapy will be proposed

Locations

Country	Name	City	State
Belarus	Scientific and Practice Center of Cardiology	Minsk

Sponsors (1)

Lead Sponsor	Collaborator
State Institution "Republican Scientific and Practical Center" Cardiology, Belarus

Country where clinical trial is conducted

Belarus, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	development of cardiovascular diseases and complications	hypertension, cardiomyopathy, arrhythmia's, myocardial infarction, heart failure	4 years