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Effect of Early Non-invasive Phrenic Nerve Stimulation on Weaning in Mechanically Ventilated Patients

Mechanical Ventilation Clinical Trial

Official title:
Effect of Early Non-invasive Phrenic Nerve Stimulation on Weaning in Mechanically Ventilated Patients：A Multicenter, Randomized Controlled Study

Clinical Trial Summary

the early application of non-invasive PNS in MV patients can increase the number of days without mechanical ventilation, delay disuse phrenic atrophy, and improve the strength of inspiratory muscle.

Clinical Trial Description

A prospective randomized controlled study included 104 patients with MV who met inclusion criteria in multiple hospital ICU units and were randomly divided 1:1 into PNS and conventional groups. The PNS group received neuromuscular electrical stimulation in addition to routine airway management, early activity and respiratory muscle training. It was verified that early non-invasive PNS could increase the number of days without mechanical ventilation for 28 days, delay disused diaphragm atrophy and improve inspiratory muscle strength. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05629819
Study type Interventional
Source Beijing Chao Yang Hospital
Contact Li Wang, B.S.Nurs
Phone 86015910268323
Email mu0mu0@yeah.net
Status Recruiting
Phase N/A
Start date January 1, 2023
Completion date December 31, 2024
View Details
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