Mechanical Ventilation Clinical Trial
Official title:
Ultrasound Evaluation of the Diaphragmatic Musculature in Mechanically Ventilated Patients in Intensive Care Unit
Muscle weakness and dysfunction are common problems in patients hospitalized in the intensive
care unit. Respiratory muscle weakness during mechanical ventilation was recognized a state
of muscular fatigue. The terminology 'ventilator-induced diaphragmatic dysfunction' (VIDD)
originally was introduced to describe these effects of mechanical ventilation and respiratory
muscle unloading on the diaphragm.
Ultrasonography is becoming increasingly popular management of ICU patients. It is a simple,
non-invasive and safe imaging technique that can be used for the assessment of distinctive
diaphragmatic characteristics.
Parameters such as amplitude and velocity of contraction, which can be assessed using M-mode
ultrasound. In addition, static and dynamic (thickening fraction during inspiration)
diaphragmatic thickness can also be measured by ultrasonography.
The aim of this study is to evaluate the effect of different modes of mechanical ventilation
on diaphragmatic thickness using ultrasonography and the relation between time of mechanical
ventilation and the percentage of change of diaphragmatic thickness in head trauma patients
subjected for mechanical ventilation (>2 days) intensive care unit.
Modes of ventilation will be used in the study are:
- Pressure controlled mandatory ventilation mode (P-CMV).
- Pressure synchronized intermittent mandatory ventilation mode (P-SIMV).
- Pressure support (PS) mode.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05921656 -
Construction and Evaluation of Airway Leakage Risk Model of Patients With Endotracheal Tube
|
||
| Recruiting |
NCT03941002 -
Continuous Evaluation of Diaphragm Function
|
N/A | |
| Withdrawn |
NCT04288076 -
The Brain and Lung Interaction (BALI) Study
|
N/A | |
| Completed |
NCT03031860 -
Semi-quantitative Cough Strength Score (SCSS)
|
N/A | |
| Completed |
NCT02545621 -
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
|
||
| Completed |
NCT02312869 -
Local Assessment of Management of Burn Patients
|
N/A | |
| Completed |
NCT01885442 -
TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
|
N/A | |
| Completed |
NCT01204281 -
Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients
|
Phase 4 | |
| Terminated |
NCT01059929 -
Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)
|
Phase 4 | |
| Completed |
NCT00824239 -
Intermittent Sedation Versus Daily Interruption of Sedation in Mechanically Ventilated Patients
|
Phase 3 | |
| Completed |
NCT00529347 -
Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern
|
Phase 1 | |
| Unknown status |
NCT00260676 -
Protective Ventilatory Strategy in Potential Organ Donors
|
Phase 3 | |
| Terminated |
NCT00205517 -
Sedation and Psychopharmacology in Critical Care
|
N/A | |
| Recruiting |
NCT04110613 -
RCT: Early Feeding After PEG Placement
|
N/A | |
| Completed |
NCT04410783 -
The Emergency Department Sedation Pilot Trial
|
N/A | |
| Recruiting |
NCT04821453 -
NAVA vs. CMV Crossover in Severe BPD
|
N/A | |
| Completed |
NCT03930147 -
Ventilation With ASV Mode in Children
|
N/A | |
| Recruiting |
NCT05029167 -
REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
|
N/A | |
| Recruiting |
NCT04849039 -
Lung Microbiota and VAP Development (PULMIVAP)
|
||
| Recruiting |
NCT06006208 -
AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport
|
N/A |