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Weakness, Muscle clinical trials

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NCT ID: NCT06441422 Not yet recruiting - Weakness, Muscle Clinical Trials

Blood Flow Restriction Training for People With Disabilities

Start date: June 15, 2024
Phase: N/A
Study type: Interventional

A large portion of the American population live with disabilities. People with disabilities can find it difficult to perform standard exercise routines. Regular exercise is necessary to be healthy, especially as people age. Lack of exercise can lead to secondary health concerns, like loss of muscle mass, diabetes, heart attack or stroke, to name a few. For exercise to be most beneficial, a certain degree of intensity must be achieved. Low load blood flow restriction training may be able to mimic the intensity of beneficial exercise without actually exercising hard. It may be a good option for people with disabilities who find it difficult to exercise.

NCT ID: NCT06020703 Recruiting - COVID-19 Clinical Trials

A Study of Healthy Microbiome, Healthy Mind

Start date: February 26, 2024
Phase: N/A
Study type: Interventional

Researchers are doing this study to find out if a high fermented food diet is tolerable, and if it will help improve quality of life after surviving a critical illness, including severe COVID-19, by promoting gut health recovery and decreasing gut inflammation.

NCT ID: NCT05967611 Recruiting - Weakness, Muscle Clinical Trials

Hip Abductor Function During Trendelenburg Test

Start date: July 25, 2023
Phase:
Study type: Observational

This study will use electromyography and dynamometry to evaluate gluteal muscle activation during the Trendelenburg hip abduction test in different hip positions.

NCT ID: NCT05941962 Recruiting - Chronic Stroke Clinical Trials

Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke

Start date: June 5, 2023
Phase:
Study type: Observational

This study wants to know if using handheld dynamometry (HHD) to test leg strength in persons who have had a stroke, will reduce mistakes and give therapists better information to use for therapy. This study will collect normal values of leg muscle peak force production, cumulative peak force production, and sustained peak force production in patients with chronic stroke.

NCT ID: NCT05877846 Recruiting - Frailty Clinical Trials

Precision Medicine and Physical Function

HMB
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The investigators aim to conduct a 12-week, single-arm, pre/post-intervention of b-hydroxy-methylbutyrate in persons aged 65 to 85 years to assess feasibility and acceptability of the intervention and study procedures, secondary outcomes of physical function and changes in multi-omics patterns, and exploratory outcomes that will allow the team to describe physical function phenotype. The investigators' primary outcomes are the: feasibility of the study procedures (including safety), feasibility of the intervention delivery, and acceptability of study procedures and measures. Secondary outcomes include: Objective and subjective physical function measures that predict disability including the 30-second sit-to-stand, knee strength, isokinetic strength, grip strength, gait speed, 400-m walk test, Pittsburgh Fatiguability, PROMIS global health-10, social support, anthropometry, National Institutes of Health (NIH) Cognitive toolbox, Automated Self-Administered 24-hour Dietary Assessment (ASA-24), Community Healthy Activities Model Programs (CHAMPS), Ultrasound Imaging, Magnetic Resonance Imaging (MRI), Changes in untargeted metabolomic profile data based on qualitative or semiquantitative analysis of the most probable detectable metabolites in laboratory samples , Discover potential metabolites that explain changes in physical function using a discovery science, precision medicine approach (discovery science approach that is exploratory)

NCT ID: NCT05876650 Completed - Pain Clinical Trials

Pilates Exercises v/s Yoga on Rounded Shoulders

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

To Compare the effects of Pilates exercises an yoga on rounded shoulders

NCT ID: NCT05815017 Recruiting - Physical Inactivity Clinical Trials

YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility

YOOMI
Start date: November 29, 2023
Phase: N/A
Study type: Interventional

Patients admitted to the hospital often develop functional impairments due to being in bed most of the day. Each day of bedrest leads to significant muscle loss. As a result, many patients become dependent on others or require rehabilitation at a facility to improve mobility and function prior to returning home. Staff in the hospital is limited and often unable to mobilize patients every day while hospitalized. The investigators are testing a new experimental gamified physical therapy exercise software to see if it can be a fun, enjoyable way to help mobilize patients without the assistance of staff. The primary aim of this pilot/proof of concept study is to determine whether gamified physical therapy software can help inpatients exercise within the safety of their own beds and preserve pre-hospitalization function.

NCT ID: NCT05725928 Recruiting - Frailty Clinical Trials

Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

The investigator proposes to conduct a randomized trial of supervised ambulation delivered by mobility technician (MT) up to three times daily, including weekends, to hospitalized medical patients. The aims of the study are to compare the short and intermediate-term outcomes of patients randomized to the intervention versus those patients randomized to receive usual care, to identify patients who are most likely to benefit from the intervention and to assess whether the intervention increases or decreases overall costs of an episode of care, including the cost of the MTs, the index hospitalization and the first 30 days post enrollment.

NCT ID: NCT05689723 Not yet recruiting - Weakness, Muscle Clinical Trials

The Effect of Spinal Manipulation on Hip Extension Strength and Jump Height

Start date: January 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to study the effects of lumbar manipulation on hip extension strength and jump height in healthy subjects. Procedures to be followed: First, the subject will be asked to complete a medical history form. Then they will be instructed on the procedure for strength and jump testing. Next, range of motion of the low back will be measured. Then hip strength will be measured using a digital handheld measurement tool. The subject will then be asked to jump as high as they can on a floor mat. The subject will then receive a sealed envelope indicating the intervention they will to receive, either the manipulation or a fake manipulation. Instructions will be provided, and the subject will be positioned on a treatment table to receive the intervention. At this point, they will either receive the manipulation or fake manipulation on the right and left side. An immediate re-test of hip strength will be taken, and the subject will again jump as high as they can on a floor mat. Follow-up measures of these tests will be completed again 20 minutes after the intervention is given.

NCT ID: NCT05670327 Completed - Weakness, Muscle Clinical Trials

Diaphragmatic Ultrasound and Weaning After Lung Transplant.

Start date: June 22, 2021
Phase:
Study type: Observational

The prevalence and adverse effect of diaphragm dysfunction (DD) after bilateral-lung transplant (LT) are still unclear, despite a well-known negative impact on weaning and outcome in other cohorts of critically ill and surgical patients. Objects: The primary aim is investigating the prevalence of DD, assessed using point-of-care ultrasound and defined as diaphragm thickening fraction (TFdi) < 29%, at the first weaning trial after LT. Secondary aims are investigating the impact of DD on weaning (defined success or failure according to pre-defined criteria, neuroventilatory efficiency (EAdi or NVE), perioperative (14-day) pneumonia, ICU length of stay (LOS), in-hospital mortality, and identifying potential risk factors for DD. Moreover, we aim to study the correlation between TFdi versus EAdi/NVE and the rapid shallow breathing index (RSBI), respectively.