Neural Operant Conditioning

Stroke Clinical Trial

Official title: Neural Operant Conditioning to Improve Walking After Stroke

Status Recruiting

Clinical Trial Summary

The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient. The main questions it aims to answer are:

• Can participants self-regulate reflex excitability

• Can participants self-regulate reflex, reduce spasticity and improve walking Participants will undergo surface stimulation to evoke spinal reflexes and will be asked to control these reflexes therefore reducing spasticity.

Researchers will compare result to able bodied participants to see if [insert effects]

Clinical Trial Description

The study purpose is to investigate the possibility and later effect of spinal reflex self-regulation in post-stroke stiff-knee gait. The intervention will consist of direct current surface stimulation of the peripheral nerves using electrical stimulation. Stimulation will evoke a motor response that will be collected through surface EMG electrodes and processed to depict a measure of the response as feedback to the participant to complete the loop of operant conditioning. The participant will attempt to modulate their responses over multiple sessions to cause this depiction to either increase or decrease its value depending on an established target.

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Related Conditions & MeSH terms

• Chronic Stroke
• Gait Disorders, Neurologic
• Gait, Hemiplegic
• Gait, Spastic
• Mobility Limitation
• Stroke
• Walking, Difficulty

• NCT number: NCT06113965
• Study type: Interventional
• Source: MetroHealth Medical Center
• Contact: Kristine Hansen, PT
• Phone: 216-957-3584
• Email: khansen1@metrohealth.org
• Status: Recruiting
• Phase: N/A
• Start date: May 31, 2024
• Completion date: May 31, 2028