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Vomiting clinical trials

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NCT ID: NCT05620641 Recruiting - Morbid Obesity Clinical Trials

Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

Start date: October 1, 2022
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the possible efficacy of ondansetron and gabapentin on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.

NCT ID: NCT05596695 Recruiting - Blood Pressure Clinical Trials

Minimisation of Blood Pressure Variability and Postoperative Nausea and Vomiting

SICK
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Intraoperative hypotension is associated with postoperative nausea and vomiting (PONV). Even though the exact mechanism linking PONV and hypotension is still unclear, a reduced intestinal tissue perfusion might trigger nausea and vomiting. Still to date only limited data evaluating intraoperative blood pressure and the incidence of PONV after general anesthesia exits. Furthermore, the effect of intraoperative blood pressure variability on the incidence of PONV has not been investigated yet. Therefore, we will test our primary hypothesis that the incidence of PONV during the early (0-2h) postoperative period will be minimized by targeting intraoperative blood pressure variability to a SPB of 120±5mmHg by using a continuous vasopressor infusion in female patients undergoing elective minor to moderate risk non-cardiac surgery.

NCT ID: NCT05590923 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Steroid-sparing Therapy (Olanzapine) Versus Dexamethasone-based Therapy for Chemotherapy-induced Nausea and Vomiting

Start date: December 7, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this research is to compare two drugs that are routinely used as standard of care for treating nausea and vomiting caused by chemotherapy. This study aims to see if the drug olanzapine is as good as the steroid drug dexamethasone for preventing nausea and vomiting after chemotherapy. Both drugs are listed as appropriate treatment options in the most recent version of National Comprehensive Cancer Network guidelines on Antiemesis.

NCT ID: NCT05546359 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients

Start date: January 18, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Randomized, double-blind, pediatric trial of amisulpride for prophylaxis of post operative nausea and vomiting

NCT ID: NCT05516953 Recruiting - Morbid Obesity Clinical Trials

Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery

Start date: August 22, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims to evaluate the possible efficacy of baclofen on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.

NCT ID: NCT05474001 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

Comparison Between IT Fentanyl and IV Granisetron in Prevention of Vomiting in CS Under Spinal Anesthesia

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Intrathecal Fentanyl Versus Intravenous Granisetron for the Prevention of Perioperative Nausea and Vomiting During Cesarean Delivery under Spinal Anesthesia

NCT ID: NCT05439057 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Effect of Remimazolam on Postoperative Nausea and Vomiting

Start date: April 13, 2022
Phase: N/A
Study type: Interventional

The present trial is to study the effect of low dose remimazolam on postoperative nausea and vomiting (PONV) in patients at risks of PONV (women, postoperative use of opioid, nonsmokers) undergoing laparoscopic cholecystectomy.

NCT ID: NCT05418244 Recruiting - Nausea Clinical Trials

Inhaled Isopropyl Alcohol for Treatment of Nausea

Start date: April 20, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.

NCT ID: NCT05417867 Recruiting - Clinical trials for Early Stage Breast Carcinoma

Association Between Changes in the Gut Microbiome and Chemotherapy-Induced Nausea in Stage I-III Breast Cancer

Start date: April 14, 2021
Phase:
Study type: Observational

This pilot study seeks to understand how changes in the bacteria composition (microbiome) of the gut may be associated with the occurrence of chemotherapy-induced nausea (CIN) in women undergoing chemotherapy for stage I-III breast cancer. Patients undergoing chemotherapy may experience nausea as a result of their treatment. Known risk factors for CIN do not explain the differences in CIN occurrence between patients, but changes in the functions of the gut microbiome may be related to the occurrence of CIN. This study collects stool samples from breast cancer patients before and after chemotherapy to evaluate how changes in the microbiome may be associated with CIN.

NCT ID: NCT05411159 Recruiting - Opioid Use Clinical Trials

Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery

OFA-PONV
Start date: June 7, 2022
Phase: N/A
Study type: Interventional

This study aimed to verify whether an Opioid-free Anesthesia (OFA) could effectively reduce the incidence of PONV after thoracoscopic-assisted surgery compared with standard general anesthesia (OA) regimens.