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Vomiting clinical trials

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NCT ID: NCT04250844 Recruiting - Vomiting Clinical Trials

Use of Intrapyloric Botulinum Injections in Children

Start date: March 10, 2020
Phase:
Study type: Observational

This study aims to evaluate the effect of intrapyloric botulinum toxin in children with feeding disorders.

NCT ID: NCT04240236 Completed - Clinical trials for Postoperative Nausea and Vomiting

Scalp Blocks Effect on Postoperative Nausea & Vomiting After Craniotomy

Start date: October 30, 2019
Phase: N/A
Study type: Interventional

In this study, the investigators hypothesize that preemptive scalp block in neurosurgical patients may decrease incidence of PONV after craniotomy through decreasing intraoperative inhalational agents' concentration and decreasing intraoperative opioids requirements, with better intraoperative hemodynamics and lesser recovery time

NCT ID: NCT04232423 Completed - Clinical trials for Complete Response Rate to Chemotherapy-induced Nausea and Vomiting Prophylaxis

Olanzapine for Chemotherapy-induced Nausea and Vomiting Prophylaxis

OLN-EME
Start date: March 1, 2020
Phase: Phase 3
Study type: Interventional

To investigate that olanzapine can reduced side effect about nausea and vomiting in women with gynecologic cancers receiving carboplatin-based regimen by using olanzapine and placebo

NCT ID: NCT04201769 Active, not recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Dexamethasone-sparing Approach Including NEPA Against Emesis Caused by Cisplatin

LUNG-NEPA
Start date: November 25, 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the possibility to reduce the total dose of dexamethasone, when administered with NEPA, to prevent chemotherapy-induced nausea and vomiting (CINV) in Non-Small Cell Lung Cancer (NSCLC) patients receiving a cisplatin-based chemotherapy

NCT ID: NCT04191694 Recruiting - PONV Clinical Trials

Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia

Start date: October 28, 2019
Phase: N/A
Study type: Interventional

Our study aims to determine if there is a difference in a self-reported incidence of nausea and vomiting in women who are given chewing gum following elective caesarean section under spinal anaesthesia compared to those who do not receive chewing gum

NCT ID: NCT04188431 Terminated - Pain, Postoperative Clinical Trials

Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children

Blueberry
Start date: November 1, 2020
Phase: Phase 4
Study type: Interventional

Tonsillectomy is one of the most frequently performed surgical interventions in children. However, it is associated with a high incidence of PostOperative Nausea and Vomiting (PONV), severe pain and haemorrhage. There is strong evidence on the efficacy of Dexamethasone in reducing the incidence of PONV and pain after tonsillectomy, which led to consider this drug as a first line treatment in routine anaesthesia practice in such surgical setting. However, in the last decade, there have been arguments about the potential role of Dexamethasone in increasing the risk of postoperative bleeding in children and studies addressing the haemorrhage risk following administration of Dexamethasone for tonsillectomy are inconclusive.Thus, this study is aimed at providing evidence for the safety profile of Dexamethasone with regard to the risk of post-tonsillectomy bleeding in children when administered as a single intraoperative dose.

NCT ID: NCT04182828 Recruiting - Post-operative Pain Clinical Trials

Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial

Start date: November 25, 2019
Phase: Phase 4
Study type: Interventional

Lidocaine is a drug that has multiple uses. One of these is that when intravenously administered it is effective in reducing post-operative pain. The aim of this study is to investigate the beneficial effects of intravenous lignocaine on reducing pain, nausea and vomiting after laparoscopic cholecystectomy. Also, by this research, we are aiming to find a suitable alternative analgesic.

NCT ID: NCT04181346 Recruiting - Nausea Clinical Trials

Pregabalin for the Prevention of Chemotherapy Induced Nausea and Vomiting

Start date: September 1, 2019
Phase: Phase 2
Study type: Interventional

phase II randomized, double-blind, placebo-controlled trial to investigate whether pregabalin can improve the complete control of nausea and vomiting (primary end point)

NCT ID: NCT04155931 Completed - Clinical trials for Postoperative Nausea and Vomiting

The Effect of Intraoperative Body Temperature on Postoperative Nausea and Vomiting in Pediatric Patients

Start date: November 7, 2019
Phase:
Study type: Observational [Patient Registry]

The aim of our study was to investigate the effects of changes in body temperature in the perioperative period on postoperative nausea and vomiting.

NCT ID: NCT04150614 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Start date: May 14, 2020
Phase: Phase 4
Study type: Interventional

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, and drug-drug and drug-disease contraindications.