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Palonosetron vs. Ondansetron for Postoperative Nausea and Vomiting in Bariatric Surgery

Pain, Postoperative Clinical Trial

Official title:
Comparison of Palonosetron and Ondansetron for the Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery

Clinical Trial Summary

Evaluate the safety and efficacy of palonosetron versus ondansetron to reduce and control post-operative nausea in bariatric surgery.

Clinical Trial Description

Postoperative nausea and vomiting (PONV) is an undesirable clinical condition that increases the likelihood of dehiscence, bleeding, pulmonary aspiration of gastric contents, and electrolyte loss that lead to increased costs, prolonged hospital stays, and delayed recovery. In recent years, selective serotonin 5-hydroxytryptamine sub-type 3 (5-HT3) receptor antagonists such as ondansetron, granisetron, palonosetron have been introduced because they are effective in the prevention and treatment of PONV in bariatric surgery. In this study, the effects of ondansetron and palonosetron on PONV in patients who undergo sleeve gastrectomy will be compared. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04533867
Study type Observational [Patient Registry]
Source Bagcilar Training and Research Hospital
Contact
Status Completed
Phase
Start date August 15, 2020
Completion date January 1, 2021
View Details
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