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Volume Overload clinical trials

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NCT ID: NCT05965934 Recruiting - Heart Failure Clinical Trials

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0

MOJAVE
Start date: July 7, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This study is a multi-center, prospective, randomized (2:1), open-label study to evaluate the safety and efficacy of DSR therapy using the Infusate 2.0 peritoneal solution (composed of 30% icodextrin and 10% dextrose) in diuretic resistant patients with HF and persistent volume overload.

NCT ID: NCT05595395 Recruiting - Volume Overload Clinical Trials

The Enteral Resuscitation In Intensive Care Pilot- Study

ERI
Start date: February 13, 2023
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to overcome the limited evidence on enteral fluid administration in intensive care medicine and to generate data for further hypothesis generation in an exploratory setting. This trial is a prospective, multicenter, randomized, parallel group, open-label study to compare the current standard of practice, the intravenous fluid administration, with a more physiological approach, the enteral fluid administration, in critically ill patients.

NCT ID: NCT05240833 Recruiting - Critical Illness Clinical Trials

VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit

AKIVEX
Start date: January 7, 2022
Phase: N/A
Study type: Interventional

A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement Therapy (RRT) during the first 28 days.

NCT ID: NCT05217342 Recruiting - Heart Failure Clinical Trials

PVP-Guided Decongestive Therapy in HF

PERIPHERAL-HF
Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.

NCT ID: NCT04921319 Recruiting - Sepsis Clinical Trials

De-resuscitation Informed by Ultrasound for Patients With Sepsis

DRI-US
Start date: April 26, 2021
Phase: N/A
Study type: Interventional

Randomized, unblinded clinical trial of 152 critically ill patients with sepsis admitted to the intensive care unit. The primary determine if using the Venous Excess Ultrasound Score (VExUS) to guide fluid deresuscitation in critically ill patients with sepsis reduces net fluid balance at 5 days as compared to usual care.