Respiratory Failure Clinical Trial
Official title:
Acute Respiratory Failure and Continuous Positive Airway Pressure Therapy in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: a Real Life Evaluation
In December 2019 a new kind of virus was identified in China as the responsible of severe
acute respiratory syndrome (SARS) and interstitial pneumonia. Severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) quickly spread around the world and in February 2020
became a pandemia in Europe.
No pharmacological treatment is actually licensed for the SARS-CoV2 infection and at the
current state of art there is a lack of data about the clinical management of the coronavirus
2019 disease (COVID-19).
The aim of this observational study is to collect the data and the outcomes of COVID-19
patients admitted in the H. Sacco Respiratory Unit treated according to the Standard
Operating Procedures and the Good Clinical Practice.
All consecutive adult COVID-19 patients admitted to our Respiratory Unit will be enrolled.
All demographic, anthropometric, laboratory, radiological, clinical and microbiological data
will be collected and analyzed according to the primary and secondary outcomes (see the
dedicated section).
During the hospitalization, patients will be treated according to the standard operating
procedure of our Respiratory Unit, such as arterial gas analysis, Rx, pharmacological
treatment, ventilation. This study is purely observational and no randomization will be
performed.
After discharge, patients a 7 days, 30 days and 6 months follow up will be assessed.
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