Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.

Status Recruiting

Clinical Trial Summary

1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. 2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation.

Clinical Trial Description

1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. All clinical samples have been collected and tested uniformly. Correlation analysis between KLK8 and age will be performed by using Statistical Package for the Social Sciences (SPSS) 22.0 software, and P<0.05 indicates a statistically significant difference. The obtained clinical data should be recorded on survey forms, and researchers should verify patient information by recording basic information such as age and gender. 2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation. All clinical samples have been collected and tested uniformly. Correlation analysis between endothelial/epithelial damage index, age and duration of mechanical ventilation will be performed by using SPSS 22.0 software, and P<0.05 indicates a statistically significant difference. The obtained clinical data should be recorded on survey forms, and researchers should verify patient information by recording basic information such as age and gender. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06367946
Study type	Observational
Source	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Contact	Lai Jiang, PhD
Phone	13817719616__
Email	jianglaimz@sina.com
Status	Recruiting
Phase
Start date	June 1, 2023
Completion date	June 30, 2027

View Details

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