Intraoperative Lung-Protective Ventilation in Neurosurgery

Status Completed

Clinical Trial Summary

The purpose of this study is to explore the effectiveness of lung-protective ventilation during general anesthesia for neurosurgical procedures on postoperative pulmonary outcome, compared with traditional ventilation.

Clinical Trial Description

After screened for preoperative risk classification of postoperative respiratory complications,360 patients undergoing elective neurosurgery are randomly assigned to two groups, lung-protective ventilation (L) and traditional ventilation(T).Patients are mechanical ventilated with either a tidal volume of 10-12 ml/kg ideal body weight (IBW,T) or 6-8ml/kg IBW with 6-8 cm H2O PEEP(L),both with recruitment maneuver (RM).Each RM consists of applying a continuous positive airway pressure of 30 cmH2O for 30 seconds. Postoperative pulmonary complications are compared between groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02386683
Study type	Interventional
Source	Capital Medical University
Contact
Status	Completed
Phase	N/A
Start date	October 2015
Completion date	November 2020

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