Intraoperative Lung-Protective Ventilation in Neurosurgery

Status Completed

Clinical Trial Summary

The purpose of this study is to explore the effectiveness of lung-protective ventilation during general anesthesia for neurosurgical procedures on postoperative pulmonary outcome, compared with traditional ventilation.

Clinical Trial Description

After screened for preoperative risk classification of postoperative respiratory complications,360 patients undergoing elective neurosurgery are randomly assigned to two groups, lung-protective ventilation (L) and traditional ventilation(T).Patients are mechanical ventilated with either a tidal volume of 10-12 ml/kg ideal body weight (IBW,T) or 6-8ml/kg IBW with 6-8 cm H2O PEEP(L),both with recruitment maneuver (RM).Each RM consists of applying a continuous positive airway pressure of 30 cmH2O for 30 seconds. Postoperative pulmonary complications are compared between groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02386683
Study type	Interventional
Source	Capital Medical University
Contact
Status	Completed
Phase	N/A
Start date	October 2015
Completion date	November 2020

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06296173` - Open Lung Protective Extubation Following General Anesthesia	N/A
Not yet recruiting	`NCT03245684` - Assisted or Controlled Ventilation in Ards (Ascovent)	N/A
Completed	`NCT03401463` - Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar	N/A
Completed	`NCT03651817` - Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg	N/A
Recruiting	`NCT03709199` - Long Term Follow up of Children Enrolled in the REDvent Study
Recruiting	`NCT03367221` - Physiological Response in Lung Transplant Recipients Undergoing Neurally Adjusted Ventilatory Assist	N/A
Completed	`NCT03056885` - Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy	N/A
Recruiting	`NCT03746236` - Transpulmonary Pressure Under Stressing Conditions
Recruiting	`NCT03719365` - Driving Pressure Variation: NAVA vs PSV	N/A
Completed	`NCT03659552` - Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular Access	N/A
Completed	`NCT02732041` - Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome
Terminated	`NCT03525691` - Enhanced Lung Protective Ventilation With ECCO2R During ARDS	N/A
Not yet recruiting	`NCT05859906` - The Effect of Two Different Intra-abdominal Pressure Applications on "Mechanical Power" in Laparoscopic Cholecystectomy
Recruiting	`NCT05977153` - CT for Personalized Mechanical Ventilation	N/A
Not yet recruiting	`NCT06334523` - Ventilation of the Extremely Premature Infants Optimized by Dead Space Washout	Phase 2
Recruiting	`NCT04484727` - "Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"
Recruiting	`NCT05991258` - Effect of End-inspiratory Airway Pressure Measurements on the Risk of VILI in Ventilated Patients
Enrolling by invitation	`NCT03951064` - Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon	N/A
Recruiting	`NCT03945409` - New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure
Completed	`NCT03817918` - A New Ultrasonographic Tool to Assess Pulmonary Strain in Patients Under One-lung Ventilation.	N/A