Vascular Function Clinical Trial
Official title:
The Effect of Chocolate on Vascular Function of Endurance Runners
The aim of this study is to examine the effects of chocolate on the vascular function of endurance runners through a crossover study involving male runners consuming both dark and white chocolate.
Status | Not yet recruiting |
Enrollment | 50 |
Est. completion date | November 20, 2024 |
Est. primary completion date | September 1, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 25 Years to 55 Years |
Eligibility | Inclusion Criteria: - Gender: Male - Age: 25-55 years - Healthy status - Active endurance runner - Regular physical activity (at least 3 times per week) - Availability on specific days and times for research sessions - Willingness and consistency Exclusion Criteria: - Allergies or Intolerances: Participants with known allergies or intolerances to chocolate or any of its ingredients. - Cardiovascular Diseases: Participants with known cardiovascular diseases or history of cardiac episodes. - Metabolic Disorders: Individuals with diabetes or other metabolic disorders that may affect glucose and insulin metabolism. - Contradictory Diet: Individuals following specific diets that may affect the study, such as high or low flavonoid diets. - Medication Use: Individuals taking medications that affect vascular function, such as antihypertensives or anticoagulants. - Smoking: Smokers or individuals who have quit smoking within the last six months. - Substance Abuse: Individuals with a history of alcohol or substance abuse. - Patients with Chronic Diseases: Individuals with serious chronic diseases that may affect the study outcomes. - Participation in Other Studies: Individuals participating in other clinical trials or research that may affect the study outcomes. - Physical Condition: Individuals who are not regular runners or who do not exercise regularly at a level similar to other participants. |
Country | Name | City | State |
---|---|---|---|
Greece | Laboratory of Sports Medicine | Thessaloniki |
Lead Sponsor | Collaborator |
---|---|
Aristotle University Of Thessaloniki |
Greece,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | CF-PWV (Carotid-Femoral Pulse Wave Velocity) | Measurement of the velocity of the pressure wave between the carotid and femoral arteries, expressed in meters per second (m/s) | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). | |
Primary | AIx (Augmentation Index) | Measurement of arterial stiffness, calculated as the difference between the first and second systolic peaks of the arterial waveform, expressed as a percentage (%) | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). | |
Primary | Exercise Time in Cardiopulmonary Exercise Testing | Total duration of exercise during cardiopulmonary exercise testing, measured in minutes. | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). | |
Primary | VO2max (Maximal Oxygen Uptake) | Maximum amount of oxygen consumed per minute during incremental exercise, expressed in milliliters per kilogram per minute (mL/kg/min) | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). | |
Primary | 5km Time | Total time taken to complete a 5-kilometer run, measured in minutes and seconds. | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). | |
Primary | 5km Speed | Average speed during a 5-kilometer run, expressed in kilometers per hour (km/h). | Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate). |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03866343 -
Restriction of Dietary AGEs to Prevent Diabetes in Overweight Individuals
|
N/A | |
Completed |
NCT02065271 -
Herbal Preparation and Glucose Homeostasis
|
N/A | |
Completed |
NCT01945970 -
Effect of Black Tea on Vascular Function
|
N/A | |
Completed |
NCT01495325 -
Effect of Woodsmoke on Vascular Function
|
N/A | |
Terminated |
NCT04239482 -
Nutritional Supplementation and Insulin Sensitivity
|
N/A | |
Completed |
NCT02273323 -
Flow Mediated Dilation in Response to Black Tea
|
N/A | |
Completed |
NCT04550026 -
Cardiovascular Effects of Heated Tobacco Products (HTP)
|
N/A | |
Completed |
NCT03849300 -
Impacts of Aquatic vs Land Walking on Vascular Health and Exercise Tolerance in Patients With Peripheral Artery Disease
|
N/A | |
Terminated |
NCT04770155 -
Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1
|
Early Phase 1 | |
Active, not recruiting |
NCT01312168 -
Endothelial Dysfunction, Monocyte Activation, and Vasculopathy in Patients With Obstructive Sleep Apnea (OSA) and Effect of 6-month CPAP Treatment
|
N/A | |
Not yet recruiting |
NCT06229873 -
Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
|
N/A | |
Recruiting |
NCT05468255 -
The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
|
N/A | |
Completed |
NCT01805063 -
Effect of Fire Suppression and Emergency Duties on Vascular Function
|
||
Completed |
NCT04700241 -
Nitrate and Brain Insulin-Sensitivity
|
N/A | |
Completed |
NCT02328339 -
Tea and Forearm Blood Flow
|
N/A | |
Completed |
NCT01575041 -
The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function
|
N/A | |
Completed |
NCT03324256 -
Energy Drinks and Vascular Function
|
N/A | |
Completed |
NCT04175457 -
The Acute Effects of E-cigarette Inhalation on Vascular Function, Microcirculation and Thrombosis
|
N/A | |
Completed |
NCT01053026 -
Evaluation of Effects of Exercise Training and ARB in DM Patients
|
N/A | |
Completed |
NCT03625596 -
Nutritional Supplements and Nitric Oxide Bioactivity
|
N/A |