Effects of COP Exercise and HIIT on Vascular Health in Young Overweight Females

Vascular Diseases Clinical Trial

Official title:

Effects of Crossover Point Exercise and High-intensity Interval Training on Vascular Health in Young Overweight Females

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05817487
• Other study ID #: EOCPEAHITOVHIYOF
• Status: Completed
• Phase: N/A
• Start date: February 18, 2019
• Est. completion date: October 25, 2019

Study information

• Verified date: April 2023
• Source: Beijing Sport University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.

Description:

In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: October 25, 2019
• Est. primary completion date: July 5, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

1. Female, 18-30 years old

2. Body mass index (BMI) < 28 kg/m2 and = 24 kg/m2

3. No exercise habit, and no recent new exercise plan

4. No contraindications to exercise

Exclusion Criteria:

1. Participates had an orthopedic or other condition that limited participation in daily exercise

2. Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer

3. Participates had smoking or alcohol behavior

Related Conditions & MeSH terms

• Overweight
• Vascular Diseases

Intervention

Behavioral:
• high-intensity interval training (HIIT)
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The training sessions in the HIIT group involved five high-intensity intervals of 4 minutes each (running or walking on a treadmill) at 85% VO2max interspersed with 3 minutes of low-intensity walking.
• crossover point(COP) exercise training
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The COP exercise training sessions involved 45 minutes of continuous exercise at the COP on a treadmill.

Locations

Country	Name	City	State
China	Beijing Sport University	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Beijing Sport University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	brachial-ankle pulse wave velocity (baPWV)	The change of baPWV before and after intervention	10 weeks
Primary	blood pressure	The change of blood pressure before and after intervention	10 weeks
Secondary	Interleukin 6 (IL-6)	The change of IL-6 level before and after intervention	10 weeks
Secondary	Homocysteine (HCY)	The change of HCY level before and after intervention	10 weeks