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Vascular Diseases clinical trials

View clinical trials related to Vascular Diseases.

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NCT ID: NCT02933957 Recruiting - Vascular Disease Clinical Trials

Chinese Arteriosclerosis Series Evaluation-She Minority Study

CASE-SMS
Start date: January 2015
Phase: N/A
Study type: Observational

Traditionally, people have always been focusing on vascular injuries by angiography. Recent years, the investigators have further known that the pathological foundation of various cardiovascular complications not only lies in the vascular lumen, but also vessel wall. Therefore, now it is possible to detect and prevent vascular disease early. There are many influencing factors on functional and structural damages of vessels, including genetic and environmental factors. The investigators have done many researches on populations of the Han nationality, which has the largest population in China. Thus, the investigators further wonder whether the function and structure of vessel differ in the She Minority of a remote southern region in China. The investigators will enroll 150 subjects of two ethnic groups respectively in the local population, namely She Minority and Han nationality. All subjects enrolled into the study will complete a questionnaire survey of the general situation and conduct vascular related examinations, including evaluation of arterial stiffness, arterial elasticity indexes, subclinical carotid atherosclerosis and biomarkers. The investigators will analysis vascular differences between the two populations and provide a theoretical basis for the specific strategies of prevention and treatment.

NCT ID: NCT02834858 Recruiting - Diabetic Foot Clinical Trials

Umbilical Cord Mesenchymal Stem Cells Infusion for Diabetes Related Vascular Complications

Start date: January 2016
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02831075 Recruiting - Diabetic Foot Clinical Trials

A Clinical Study Using Adipose-derived Stem Cells for Diabetic Foot

Start date: January 2015
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02827071 Recruiting - Clinical trials for Macular Degeneration

Ocular Imaging Study Using Advanced OCT

Start date: July 2016
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate this AngioScan angiography software on patients with various retinal vascular disorders. The advanced OCT instrument is an FDA approved clinically used camera, but the AngioScan angiography software is not FDA approved. Investigators would like to know if this imaging device and software can improve the quality of images and visualization of imaged tissues and whether they are useful in the diagnosis and treatment of eye diseases. Images collected in this study may be compared to other images collected as part of standard of care on the same patient (OCT, FA, AF, Fundus).

NCT ID: NCT02820233 Recruiting - Heart Failure Clinical Trials

Studies of Neuregulin/ERBB Signaling in Human Heart

Start date: June 2015
Phase:
Study type: Observational

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

NCT ID: NCT02815176 Recruiting - Clinical trials for Central Serous Chorioretinopathy

Angiographic Characteristics of CSC, PCV Patients and Thrombotic Bio-markers

Start date: June 2016
Phase: N/A
Study type: Observational

Thrombotic biomarkers and angiographic characteristics were compared among the de novo patients of central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV) and the control.

NCT ID: NCT02805023 Recruiting - Clinical trials for Peripheral Arterial Disease

BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)

EnEPC-CLI
Start date: June 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Evaluate the feasibility of an autologous cell preparation composed of a mixture of cells enriched for endothelial progenitor cells (EnEPCs) and multipotent adult hematopoietic stem/progenitor cells (HSPC) (BGC101), in the treatment of patients suffering from peripheral arterial disease (PAD) with critical limb ischemia (CLI) who have not responded to optimal pharmacological treatment or control of risk factors and/or had a revascularization failure, and do not have the option of further revascularization treatment.

NCT ID: NCT02798731 Recruiting - Clinical trials for Cardiac Allograft Vasculopathy

Physiologic Assessment of Microvascular Function in Heart Transplant Patients

Start date: May 2016
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to evaluate the impact of early microvascular disease assessed by coronary physiologic indices such as fractional flow reserve (FFR), coronary flow reserve (CFR), index of microvascular resistance (IMR) on future occurrence of cardiac allograft vasculopathy (CAV) in heart transplant recipients.

NCT ID: NCT02796079 Recruiting - Diabetic Foot Clinical Trials

A Clinical Study Using Autologous Bone Marrow Stem Cell for Diabetes Related Vascular Complications

Start date: January 2015
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02638727 Recruiting - Vascular Disease Clinical Trials

Assessment of Short-term Effect of L-Citrulline on Endothelial Function and Vasodilation in Known CAD Patients

Start date: December 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy of oral L-Citrulline on endothelial function and vasodilation in patients with coronary artery disease(CAD) by evaluating the brachial artery diameter in the antecubital area by ultrasonography.