Inflammation Clinical Trial
Official title:
The Folic Acid and Carotid Intima-Media Thickness (FACIT) Study: A Randomized Controlled Trial
The purpose of this study is to determine if folic acid supplementation can slow down atherosclerotic progression, age-related cognitive decline and age-related hearing loss.
Low levels of B vitamins, in particular folate, and high levels of plasma total
homocysteine, have been associated with a variety of age-related diseases and disorders,
including cardiovascular disease, dementia and hearing impairment. Extra folate, for example
in the form of folic acid, is known to decrease the concentrations of plasma total
homocysteine.
We examined whether 0.8 mg/d folic acid could slow down atherosclerotic progression and the
above mentioned age-related processes.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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