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Clinical Trial Summary

The purpose of the open-label INDIGO-study is to examine whether a first line individualized treatment strategy based on DNA and RNA analyses from the patient's tumor is feasible. Moreover, to involve the patient further in their treatment via patient-reported outcomes (PRO) measurements in a value-based healthcare setup with simultaneous analyses of the financial costs of this strategy. The patients are assigned into 4 treatment arms according to the results of their DNA and RNA analyses. All patients receive electronic questionnaires regarding symptoms and side effects weekly and questionnaires regarding quality of life monthly. Based on each patient's answers of the questionnaires the patient receives advices in the app to reduce the symptoms and side effects or the patient is instructed to contact the hospital. The hypothesis: Basing the choice of first-line treatment for DNA mutations and RNA profiles in a heterogeneous patient population increases the overall response rate for the total population to 30% compared to 10% for historical cohorts.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04644432
Study type Interventional
Source Herlev and Gentofte Hospital
Contact Anne Kirstine H Moeller, MD, PhD
Phone +4538681083
Email anne.kirstine.hundahl.moeller@regionh.dk
Status Recruiting
Phase Phase 2
Start date March 6, 2020
Completion date September 6, 2022

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