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Urolithiasis clinical trials

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NCT ID: NCT04490343 Active, not recruiting - Urolithiasis Clinical Trials

Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm

URO DLIR
Start date: July 21, 2020
Phase: N/A
Study type: Interventional

Urolithiasis has an increasing incidence and prevalence worldwide, and some patients may have multiple recurrences. Because these stone-related episodes may lead to multiple diagnostic examinations requiring ionizing radiation, urolithiasis is a natural target for dose reduction efforts. Abdominopelvic low dose CT, which has the highest sensitivity and specificity among available imaging modalities, is the most appropriate diagnostic exam for this pathology. The main objective of this study is to evaluate the diagnostic performance of ultra-low dose CT using deep learning-based reconstruction in urolithiasis patients.

NCT ID: NCT04398251 Enrolling by invitation - Urolithiasis Clinical Trials

A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.

Start date: April 10, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study was to explore the effects of uric acid control on stone recurrence and renal function in patients with calculi of hyperuricemia through a prospective controlled study.

NCT ID: NCT04387617 Completed - Urinary Stone Clinical Trials

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

Start date: February 15, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine if CBD oil has any effect on decreasing postoperative pain control following ureteroscopy for urinary stone disease, and to determine if CBD oil has any effect in decreasing the amount of postoperative opioids (commonly used drug) used by patients after undergoing ureteroscopy for urinary stone disease.

NCT ID: NCT04380675 Completed - Urolithiasis Clinical Trials

Music During ESWL for Entire Treatment

Start date: November 2, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if music listening relieves pain and discomfort during Extracorporeal Shock-Waves Lithotripsy (ESWL).

NCT ID: NCT04354181 Completed - Urolithiasis Clinical Trials

Urine Biomarker for Stone Recurrence

Start date: July 24, 2020
Phase:
Study type: Observational

Despite the advent of treating stones with Extracorporeal Shock Wave Lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL), the recurrence rate for renal stones remains high and this may be due to poor compliance of patients with dietary and fluid advice, age, metabolic abnormalities, medicines and the formation of "new stones" from clinically insignificant residual fragments (CIRF). Though some patients become stone-free after ESWL/PCNL or open surgeries, the majority develop "new stones" and it is difficult to predict when these stones will recur until either they have imaging perform or they developed symptoms. However, the use of regular imaging for monitoring will be costly and involve radiation exposure. Therefore, a diagnostic tool is needed to enable the clinician and/or patient to monitor for stone recurrence. In the previous studies, some urine markers were identified that are related to stone formation. The relationship of these urine markers with the recurrence of renal stone will be further explore in this study. Also, potential markers that could predict stone recurrence will be identified, and hence earlier intervention could be offered to patients.

NCT ID: NCT04346485 Recruiting - Urolithiasis Clinical Trials

Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers

Start date: March 13, 2020
Phase: N/A
Study type: Interventional

The authors hypothesize that the RIRS using 150-microm Tm-fiber laser is superior than fiber with larger diameters, as 200-microm Tm-fiber laser or 200-microm holmium fiber laser, in such points as follows: - decreasing surgery time and laser-on time due to possibility of 4.3 fold ablation efficacy increase, which has been shown by Andreeva et al.; - increasing the flexible ureteroscope tip deflection lower pole stones availability; - decreased risk of complications and a better irrigation and visualization due to better irrigation with smaller fiber; - increasing of lithotripsy efficacy and laser beam density by lowering of beam focal spot due to using of lesser fiber diameter

NCT ID: NCT04340037 Completed - Infection Clinical Trials

Prediction of Sepsis After Percutaneous Nephrolithotomy

Start date: March 1, 2019
Phase:
Study type: Observational

We aim to determine the preoperative predictors of sepsis after percutaneous nephrolithotomy (PCNL) in patients with unilateral, solitary and proximal ureteral stones.

NCT ID: NCT04338451 Completed - Urolithiasis Clinical Trials

Music During ESWL for Half Treatment

Start date: February 2, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if music listening relieves pain and discomfort during Extracorporeal Shock-Waves Lithotripsy (ESWL).

NCT ID: NCT04332861 Completed - Sepsis Clinical Trials

Evaluation of Infection in Obstructing Urolithiasis

eIOU
Start date: September 3, 2019
Phase:
Study type: Observational

Obstructing urolithiasis can be life-threatening in the setting of urinary tract infection. The purpose of this study is to identify and validate risk factors and markers for the presence of infection and development of sepsis among patients with obstructing urolithiasis.

NCT ID: NCT04284241 Recruiting - Urolithiasis Clinical Trials

Parents' Health-Education Handbook in Preventing Pediatric Urolithiasis Formation

Start date: November 20, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to estimate the role of Parents' Health-Education Handbook in preventing pediatric urolithiasis. This study is designed as an unmatched clusters randomized intervention trial. A total of 171 villages and communities in Shufu Count in Kashgar Region of China are assigned to intervention group or control group by a simple random sampling technique with a rate of 1:1. Newborns and their parents are assigned to intervention group or control group as their villages or communities. And at least 2314 newborns are needed in this study. Participants include newborns and their parents. The baseline of newborns includes demographic data, blood cell analysis, urinary tract ultrasonographic examination. Newborns' parents will be asked to answer a questionnaire which regarding the knowledge, attitudes, and practices (KAP questionnaire, estimated by scores) related to pediatric stone. Parents in intervention group will undergo and active health education by the investigator with " Parents' Health-Education Handbook", while parents in control group are without the program. Newborns are invited to undergo blood cell analysis, urine analysis and urinary tract ultrasonographic examination separately when they are one, two and three years old. Their parents will be asked to answer the same KAP questionnaire at the same time. The incidence of urolithiasis is evaluated and compared between the two groups. Improvement of knowledge, attitudes, and practices (KAP questionnaire) related to pediatric stone of parents are evaluated. Association between urolithiasis incidence and improvement of scores in KAP questionnaire are evaluated.