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Urolithiasis clinical trials

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NCT ID: NCT04110574 Not yet recruiting - Urinary Calculi Clinical Trials

Computed Tomography Evaluation of Urinary Stones Densities Compared to in Vitro Analysis of Its Chemical Composition

Start date: March 30, 2020
Phase:
Study type: Observational

The ability to predict stone composition, which influences patient treatment, depends on the accurate measurement of CT attenuation of stones. We will study the effects of stone composition, stone size, and scan collimation width on the measurement of attenuation in vitro.

NCT ID: NCT04080973 Not yet recruiting - Osteopenia Clinical Trials

Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia

Start date: October 2019
Phase: N/A
Study type: Interventional

Patients suffering from acute renal colic are evaluated by non contrast computerized tomography with excellent identification rates of urinary stones. The scan also covers the bones of the ribs, spine and pelvis, allowing measurements of the bone density and identifying early osteopenic changes. Bone demineralization is associated with metabolic changes such as hypercalcemia or hypercalcuria. In this study the investigators will look for correlation between kidney stones, osteopenic bone changes and metabolic abnormalities.

NCT ID: NCT04073719 Not yet recruiting - Clinical trials for Kidney Stones, Urolithiasis, Hypocitraturia

Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)

APUL
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether certain beverages can increase urinary citrate levels in healthy individuals with no history of kidney disease.

NCT ID: NCT03805542 Not yet recruiting - Urolithiasis Clinical Trials

Treatment of Calculous Pyonephrosis With 0.5% Iodophors for I-stage PCNL

Start date: August 2019
Phase: N/A
Study type: Interventional

Calculous Pyonephrosis is a special type of urinary tract calculi, which is also common in clinical practice. If pyonephrosis is not treated in time, it will have a serious impact on the kidney function. Most stone operations can be performed in one stage, but there is still some controversy about whether PCNL can be performed in first stage for calculous pyonephrosis. The traditional idea is that nephrostomy should be performed first to induce pyuria caused by influenza, and then stone removal should be done in the second stage. However, I-stage nephrostomy and drainage and II-stage lithotripsy can also lead to prolonged hospitalization, increased medical costs and increased family burden. Based on the current treatment status of pyonephrosis patients, previous animal experimental results and volunteers' blood iodine absorption status, we intend to design a clinical trial of Stage-I percutaneous nephrolithotomy(PCNL) after iodophor disinfection of renal collecting system. Iodophor, also known as povidone iodine, is composed of iodine and polyol ether surfactants. Iodophor disinfectant is a disinfectant with iodine as its main ingredient. It has strong bactericidal power and broad antimicrobial spectrum. It can kill viruses, bacterial propagules, fungi, protozoa, etc. 0.5% iodophor disinfectant (containing effective iodine 5000mg/L) can form a very thin bactericidal film on the wound surface and release it slowly and persistently. At present, clinical studies on calculous pyonephrosis at home and abroad are mostly single-center, small sample studies, and lack of randomized controlled clinical trials. In view of the current situation and animal experimental results, we intend to carry out a clinical trial of "iodophor treatment of pyonephrosis and one-stage operation" in order to benefit patients with calculous pyonephrosis.

NCT ID: NCT03220516 Not yet recruiting - Urolithiasis Clinical Trials

Single-use Digital Flexible Ureteroscope vs Nondisposable Fiber Optic vs Digital Ureteroscope

Start date: August 2017
Phase: N/A
Study type: Interventional

The aim of this trial is to compare the safety, efficacy and cost effectiveness of the three types of scopes.

NCT ID: NCT02949323 Not yet recruiting - Urinary Stone Clinical Trials

Etiological Diagnosis of Urinary Stone in Chinese Children

Start date: November 2016
Phase: N/A
Study type: Observational

The incidence of nephrolithiasis in children has been reported to increase by approximately 6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent rate. Investigators aimed to determine the metabolic risk factors in Chinese children through metabolic evaluation. In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.

NCT ID: NCT02214836 Not yet recruiting - Urolithiasis Clinical Trials

Ultrasound Imaging of Kidney Stones and Lithotripsy

Start date: October 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether new software processing of ultrasound images can improve detection and size determination of kidney stones.

NCT ID: NCT01361516 Not yet recruiting - Urolithiasis Clinical Trials

Comparison of General Anaesthesia and Sedation on the Stone Fragmentation in Lithotripsy

Start date: July 2011
Phase: N/A
Study type: Interventional

The aim of the study is to compare the impact intravenous sedation versus general anesthesia on the efficacy of stone fragmentation in extracorporeal shock wave lithotripsy treatment.