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Urolithiasis clinical trials

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NCT ID: NCT03656913 Terminated - Nephrolithiasis Clinical Trials

Validation of Low Dose CT for Diagnosis of Urolithiasis

Start date: November 30, 2018
Phase: N/A
Study type: Interventional

The investigators have developed an extremely low dose renal computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of a single view abdominal radiograph. The investigators plan to test this exam in patients with known or suspected urolithiasis undergoing clinically indicated CT.

NCT ID: NCT03638336 Withdrawn - Lithiasis, Urinary Clinical Trials

Evaluation of the Performance of a Robotic Flexible Ureteroscopy (ILY) in Laser Treatment of Nephrolithiasis

EASILY
Start date: October 2018
Phase: N/A
Study type: Interventional

In this pilot study, we wish to evaluate the performance of a robotic flexible ureteorscopy (ILY) in the treatment of nephrolithiasis in the superior excretory system

NCT ID: NCT03636516 Completed - Urolithiasis Clinical Trials

Effect of Double J Stent on Outcomes of Extracorporeal Shock Wave Lithotripsy

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Background: Many studies showed that stone-free rates (SFRs) after extracorporeal shock wave lithotripsy (SWL) might be related to both the patient (body mass index; BMI, skin-to-stone distance; SSD), and stone related factors (location, stone size, and stone density). However, the possible effect of pre-stenting on success as well as complication rates after SWL has not been evaluated in detail to date. Taking this fact into account, the effect of pre-stenting on the outcomes of SWL treatment in renal stones must be evaluated in the absence of possible effects induced by the patient and stone-related factors. Aim: To evaluate the effect of double J (JJ) stents on SWL treatment of moderate sized (15-25-mm) renal pelvic stones. Study design: Randomized prospective study Methods: Between January 2016 and December 2017, a total of 152 adult patients who were planned to undergo SWL for a single radiopaque renal pelvic stone were included in the study. Patients with solitary kidney, congenital abnormality, skeletal tract abnormalities, previous urinary system surgery, hydronephrosis (grade 2 or more), untreated urinary tract infection, bleeding disorder, and suspected pregnancy were excluded. The remaining 114 patients were randomly divided into two groups; nonstented and stented. Twenty-two patients whose stone could not be fragmented despite 3 consecutive sessions were also excluded from the study. A total of 92 patients (54 non-stented and 38 stented) were included in the final analysis.

NCT ID: NCT03614052 Terminated - Urolithiasis Clinical Trials

Tamsulosin as Adjuvant Treatment Prior to Endoscopic Ureterolithotomy

Start date: June 1, 2018
Phase: Phase 4
Study type: Interventional

This a study aiming to compare treatment with tamsulosin versus placebo in patients undergoing endoscopic treatment for urolithiasis. The main outcome is the rate of stone free patients.

NCT ID: NCT03526458 Completed - Surgery Clinical Trials

Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

The primary objective of this study is to compare the time to acceptable stone fragmentation during clinical use of the holmium laser when using energy settings 0.2J vs 0.8J. The hypothesis is that holmium laser energy settings 0.8J will require less time than lower energy settings 0.2J for fragmenting urinary stones. The clinical practice is to treat urinary stones until the stone is reduced to fragments ≤ 2 mm in size. This is determined by using the laser fiber which is 273 microns to visually estimate the size of the resultant fragments as described by Patel et al, J Endo 2014. Investigators will standardize the effect of stone size by creating a ratio of stone size to treatment time. In this study, the frequency is set at 15Hz. Thus, the study contains two arms: 0.2J&15Hz, and 0.8J&15Hz. Patients will be randomized into the two groups by the ratio of 1:1.

NCT ID: NCT03512600 Completed - Lithiasis, Urinary Clinical Trials

Study of the Effects of the Consumption of Different Products Cocoa Derivatives at the Risk of Crystallization of Uric Acid in Urine of Volunteers.

Start date: September 4, 2017
Phase: N/A
Study type: Interventional

The present study aims to assess the effectiveness of theobromine, -product present in high proportion in the cacao-, to prevent the development of uric acid kidney stones.

NCT ID: NCT03349099 Completed - Urolithiasis Clinical Trials

Impact Ureteral Sheath Design During Ureteroscopy

Start date: June 27, 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available. The investigators will compare the ability of sheaths to access the kidney through the ureter and will compare damage done to the ureter after completion of the procedure. Access sheaths are standard of care for this procedure; this study seeks to optimize outcomes for patients. Patients undergoing ureteroscopy who do not have ureteral stents in place and who have not had an ipsilateral procedure within 90 days will be recruited and consented.

NCT ID: NCT03343743 Completed - Urolithiasis Clinical Trials

Changes in Renal Papillary Density After Hydration Therapy in Calcium Stone Formers

Start date: June 2013
Phase: N/A
Study type: Interventional

Patients with recurrent calcium oxalate stones undergoing endourological procedures for renal stones at our institution from June 2013 to June 2014 were considered eligible for enrolment. Enrolled patients underwent a baseline unenhanced CT scan before the urological procedure; after endoscopic removal of their stones, the patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C <200 mg/L) for at least 12 months. Finally, the patients underwent a follow-up unenhanced CT scan during hydration regimen.

NCT ID: NCT03339388 Terminated - Urinary Stone Clinical Trials

Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stone Disease

Start date: December 8, 2017
Phase: N/A
Study type: Interventional

This is a single arm, multi-center study to assess the safety and efficacy of a form of extracorporeal lithotripsy, called the Enhanced Lithotripsy System, to treat urinary stones.

NCT ID: NCT03307096 Recruiting - Clinical trials for Surgery--Complications

Evaluation of Two Different Treatments for Lower Pore Renal Stone: Microperc Vs FURS

Start date: November 17, 2017
Phase: N/A
Study type: Interventional

This is a prospect, randomized control trial to evaluate merits between microperc and FURS for lower pole renal stone