Urinary Tract Infection Clinical Trial
Official title:
A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder
Symptomatic urinary tract infections (UTIs) are one of the main causes of morbidity and the
main cause of re-hospitalization in subjects with neurogenic bladder. Long-term antibiotic
therapy increases the risk of multi-resistant bacterial infections, without reducing the
rate of symptomatic UTIs. Our non-comparative preliminary study has shown that Weekly Oral
Cyclic Antibiotic Programme (single, weekly dose of antibiotic X on even weeks, and
antibiotic Y on odd weeks) seem to drastically reduce both the number of symptomatic UTIs
and the number of hospitalizations in patients with neurogenic bladder, without affecting
bacterial ecology.
The objective of this study is to validate this preliminary work with a large-scale
randomized, parallel-group, multicenter study.
n/a
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