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Urinary Tract Infection clinical trials

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NCT ID: NCT04882085 Completed - Bacteremia Clinical Trials

Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults

Start date: August 26, 2021
Phase: Phase 4
Study type: Interventional

This is an open-label, randomized, multi-center, interventional, active-controlled Phase 4 study to evaluate the efficacy and safety of CAZ-AVI versus BAT in the treatment of infected participants with selected infection types (Hospital Acquired Pneumonia [HAP] (including Ventilator-Associated Pneumonia [VAP]); Complicated Urinary-Tract Infection [cUTI]; Complicated Intra-Abdominal Infection [cIAI]; Bloodstream Infection [BSI]) due to carbapenem-resistant Gram-negative pathogens in China.This study will be an estimation study. The statistical inference will be based on point estimate and confidence interval.

NCT ID: NCT03235947 Completed - Clinical trials for Urinary Tract Infection

Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients

PERIFOS
Start date: September 7, 2016
Phase: Phase 4
Study type: Interventional

A clinical controlled, randomized and double blind trial that included adult patients (≥18 years) receiving kidney transplantation (KT) at the INCMNSZ. The intervention group will receive disodium fosfomycin 4 g intravenously in three moments: preoperative of transplant surgery, prior to removal of the urinary catheter and finally prior to removal of ureteral catheter. The control group will receive placebo in the same moments. Both groups will receive prophylaxis standard for urinary tract infection (UTI), with trimethoprim/sulfamethoxazole 160/800 mg per day. This prophylaxis will be administered once the estimated glomerular filtration rate is greater than 30 mL/min/1.73m2. The primary objective is to compare the average number of episodes of UTI´s and asymptomatic bacteriuria in both groups after 7 weeks of follow-up. The secondary objectives are to know the incidence of asymptomatic bacteriuria, the incidence of hospitalizations for IVU, the days of hospital stay, the pattern of bacterial resistance, the safety of disodium fosfomycin, and assessment of the function of the graft and rejection rate.

NCT ID: NCT03042273 Completed - Clinical trials for Urinary Tract Infection

High Strength Cranberry Supplementation for Prevention of Recurrent Urinary Tract Infection

Start date: May 15, 2017
Phase: Phase 2
Study type: Interventional

This clinical trial is a Phase 2, multicenter, placebo-controlled, double-blind, parallel-arm study to evaluate the efficacy and safety of High Strength Cranberry (500mg Pacran®) in preventing UTI (cystitis) in women with a history of recurrent UTI (rUTI).

NCT ID: NCT02882256 Completed - Clinical trials for Urinary Tract Infection

Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department

Start date: June 2016
Phase: N/A
Study type: Interventional

Patients seen in the ED with either a laceration, minor head injury, or urinary tract infection will be randomized to one of two groups. Both groups will receive the standard written discharge instructions; in addition, one group will watch video discharge instructions. Each patient will be asked to complete a short survey with questions related to the discharge instructions received in the ED, and will be called 5-7 days after the ED visit to ask questions about discharge instructions and the ED visit.

NCT ID: NCT02856633 Completed - Hypertension Clinical Trials

Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station

Start date: July 2016
Phase: N/A
Study type: Observational

The study objective is to satisfy the testing requirements for the Qualcomm Tricorder XPRIZE Competition. This requires an oversight model using the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station to continuously monitor the patient's five core vital signs and to detect the health conditions required by the competition.

NCT ID: NCT02797613 Completed - Clinical trials for Urinary Tract Infection

Restricted Reporting for Positive Urine Cultures

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the laboratory for culture results. The restricted report may reduce the rate of inappropriate treatment of AB.

NCT ID: NCT02786810 Completed - Clinical trials for Urinary Tract Infection

Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The study will be evaluating the efficacy and safety of a contrast drug in pediatric renal ultrasound.

NCT ID: NCT02785445 Completed - Diabetes Clinical Trials

Healthy.io Method Comparison & User Performance Study

Start date: October 2015
Phase: N/A
Study type: Interventional

The objectives of the Healthy.io Method Comparison and User Performance Study are: 1. To evaluate the performance of Dip.io Device in comparison to the ACON U500 Mission® U500 Urine Analyzer. 2. To evaluate the user performance of Dip.io Device under actual use conditions (home environment) based on a user questionnaire and rating scale.

NCT ID: NCT02751073 Completed - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy

Start date: February 2016
Phase:
Study type: Observational

The purpose of this study is to learn more about the microbes (bacteria) that live in the vagina and the bladder. The investigators are doing this research study to understand the relationship between microbes (the microbiome) and the occurrence of urinary tract infection following surgical removal of the uterus and pelvic organ prolapse repair. The investigators expect Lactobacillus and Gardnerella will be the dominant organisms for most women. Non-Lactobacillus dominant microbiome communities will be more common in women who ultimately develop postoperative urinary tract infection.

NCT ID: NCT02742636 Completed - Clinical trials for Urinary Tract Infection

When is the Best Moment to Remove the Urinary Catheter After Laparoscopic Hysterectomy?

MUCH
Start date: May 31, 2016
Phase: N/A
Study type: Interventional

Objective: The aim of this study is to evaluate if direct removal of the urine catheter after an laparoscopic hysterectomy (total laparoscopic hysterectomy and laparoscopic supracervical hysterectomy) is associated with similar (or better) outcomes compared to delayed catheter removal after surgery, which is the current treatment. In addition, we want to investigate patient's experience on this subject. Study design: Randomized Controlled trial, non-inferiority study. Study population: Women older than 18 years old, who are a laparoscopic hysterectomy for benign indication or low-grade malignancy. Intervention: - Group A (treatment group): the patients in this group will have their catheter directly removed in the OR after LH. - Group B (control group): the patients in the control group will have their catheter removed according to the regular protocol of the hospital (at least 6 hours in place).