Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT04110574
Other study ID # CT of urinary stones densities
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date March 30, 2020
Est. completion date October 30, 2022

Study information

Verified date February 2020
Source Assiut University
Contact Somia Usama, Master
Phone 01060101215
Email somiaumrm@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The ability to predict stone composition, which influences patient treatment, depends on the accurate measurement of CT attenuation of stones. We will study the effects of stone composition, stone size, and scan collimation width on the measurement of attenuation in vitro.


Description:

Recently, the use of noncontrast spiral computerized tomography (NCCT) has gained widespread acceptance in the evaluation of urinary stone patients. It has long been used clinically to evaluate the causes of radiolucent filling defects using Hounsfield units (HU) to distinguish calculi from tumor or blood clots, and to identify nonurologic causes of flank pain (Smith R etal ). Urinary stones have a significantly higher CT attenuation than the surrounding soft tissues and are virtually always visible on NCCT. Knowing the composition of a urinary calculus is frequently a key factor in determining its most appropriate management. Should the urine be alkalinized? Will the stone be amenable to extracorporeal shock wave lithotripsy (ESWL), or should ureteroscopy or percutaneous lithotripsy be attempted? Different techniques have been used to assist in determining the correct chemical composition of calculi. Urine pH, urinary crystals, prior stone history and the presence of urea-splitting organisms (Ramakumar S,etal). Several in vitro studies have suggested that NCCT can demonstrate measured differences in radiodensity among different urinary stones (Mitchenson HD etal,).With these clinical problems in mind, we sought to determine whether the composition of urinary calculi could be predicted by their CT characteristics in an attempt to find out the best technique for distinguishing the various stones compositions, provided that it is clinically practical and would not require repeated imaging of the patients.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 100
Est. completion date October 30, 2022
Est. primary completion date September 1, 2022
Accepts healthy volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Any Age will be included .

- Patient with suspected or known urinary stone disease.

- Eligible for doing NCCT.

- Giving written consent to participate

Exclusion Criteria:

- Patient with classical NCCT contraindication like morbid obesity and pregnancy .

- Patients with urinary stones will be treated by ESWL

- Refusal participation .

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Assiut University

Outcome

Type Measure Description Time frame Safety issue
Primary comparison of CT densities of urinary stones with its chemical composition determination whether the composition of urinary calculi could be predicted by their CT characteristics in an attempt to find out the best technique for distinguishing the various stones compositions . Baseline
See also
  Status Clinical Trial Phase
Recruiting NCT04924790 - The Effect of the COVID-19 on Patient Preferences and Decision Making for Obstructive Urinary Stone Interventions
Recruiting NCT05701098 - SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) N/A
Recruiting NCT05574517 - Tubeless Percutaneous Nephrolithotomy Without Reverse Insertion of a Ureteral Catheter N/A
Withdrawn NCT00388271 - Use of Alfuzosin in Stone Treatment With ESWL Phase 3
Recruiting NCT02298465 - ESWL for Distal Ureteric Stone: Supine Versus Prone N/A
Active, not recruiting NCT01973088 - Screening and Identification of Human Urate Transporter hURAT1 MicroRNA N/A
Recruiting NCT01884870 - Silent Ureteral Stone: Impact on Renal Function and Kidney Anatomy N/A
Active, not recruiting NCT00575432 - Evaluation of Kidney Function by Multi-modal Magnetic Resonance Imaging and Spectroscopy
Completed NCT05027971 - Flexiva Pulse Registry
Terminated NCT00199524 - Use of a Ureteral Access Sheath During Ureteroscopy and Its Effect on Stone Free Rate Phase 4
Recruiting NCT05048706 - SP TLF Versus Ho:YAG Laser N/A
Recruiting NCT02594631 - Shock Wave Lithotripsy Versus Visual Cystolitholapaxy in The Management of Patients Presenting With Calcular Acute Urinary Retention: A Randomized Controlled Trial. Phase 4
Completed NCT00857090 - Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones Phase 1/Phase 2
Completed NCT04112160 - Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal Phase 2
Completed NCT04594161 - Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis N/A
Not yet recruiting NCT04796792 - Ultrasound to Facilitate Stone Passage N/A
Recruiting NCT05270421 - Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi Phase 3
Completed NCT02983409 - Analysis the Relationship Between the Abdomen CT and Outcomes in Acute Urinary Stone Patients N/A
Not yet recruiting NCT00397397 - Comparative Treatment Study in Patients With Lower Ureteral Stones Phase 0
Completed NCT00199459 - Proteomic Study of Urinary Stone Disease N/A