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Urinary Bladder, Neurogenic clinical trials

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NCT ID: NCT05840874 Enrolling by invitation - Child, Only Clinical Trials

Complications of Enterocystoplasty in Children

AVPED
Start date: March 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood. The main question[s] it aims to answer are: - what kind of complications are there - the kind of complications depending on the type of enterocystoplasty Participants data will be collected in the medical field. There is no comparison group.

NCT ID: NCT05740527 Enrolling by invitation - Clinical trials for Urinary Bladder, Neurogenic

Ambulatory Closed-loop Stimulation for Bladder Control

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Individuals with spinal cord injury (SCI) develop neurogenic detrusor overactivity (NDO), resulting in urinary incontinence, decreased bladder capacity, and reduced quality of life. Current treatments incompletely address the problem and have unwanted side effects. Therefore, an alternative approach is needed. Electrical stimulation of the genital nerves (GNS) can inhibit NDO, improving bladder capacity and urinary continence. However, an automated closed-loop bladder feedback system, which currently does not exist, is necessary for individuals with SCI and NDO to utilize this therapy. The researchers have developed a custom algorithm to detect bladder contractions in real time, which requires only a bladder pressure signal. Our collaborators have developed a wireless, catheter-free bladder pressure sensor, called the UroMonitor, that was recently approved for testing in human participants. The goal of this project is to evaluate the potential feasibility and effectiveness of automated closed-loop GNS to inhibit unwanted bladder contractions using our custom algorithm and the wireless UroMonitor sensor. This project represents the next logical step toward improving or restoring bladder control using existing or emerging approaches to meet an important need for individuals with SCI. Successful completion of this project will motivate advancing a closed-loop approach using our custom algorithm and wireless bladder pressure sensor.

NCT ID: NCT05688644 Enrolling by invitation - Overactive Bladder Clinical Trials

Sacral Neuromodulation in Neurogenic Patients

Start date: December 19, 2021
Phase:
Study type: Observational

The goal of this observational study is to evaluate efficacy and safety of sacral neuromodulation in neurogenic patients compared to non-neurogenic (idiopathic) patients. [. The main question[s] it aims to answer are: - determine efficacy and safety of the therapy in neurogenic patients. - compare outcomes of the therapy to idiopathic patients. If there is a comparison group: Researchers will compare the outcomes of the therapy between the neurogenic and non-neurogenic subset of patients.

NCT ID: NCT05482347 Enrolling by invitation - Neurogenic Bladder Clinical Trials

Educational Video for Neurogenic Bladder

Start date: March 8, 2023
Phase: N/A
Study type: Interventional

This study is designed to assess the efficacy of educational materials in parents of children with neurogenic bladder considering surgical reconstruction. Focus groups were conducted with neurogenic bladder patients and their families in which participants were asked questions about expectations, fears, medical understanding, unexpected challenges, and persistent questions regarding reconstructive surgery for neurogenic bladder. Analysis of this qualitative data was used to create educational materials (such as animated videos) and decision-making tools for families of children with neurogenic bladders who are trying to decide what treatment option is right for them, and to better prepare them for what lies ahead. This study specifically aims to investigate the effect of an educational video on participants' knowledge of neurogenic bladder and surgical management.

NCT ID: NCT05312138 Enrolling by invitation - Clinical trials for Neurogenic Bladder Dysfunction

Multiple Sclerosis and Overactive Bladder Treatment

Start date: June 8, 2021
Phase: N/A
Study type: Interventional

Urinary symptoms are frequently seen in patients with Multiple Sclerosis (MS). Early evaluation of the patients in terms of the urinary system, planning the appropriate treatment and following up at regular intervals are extremely important in terms of preventing urinary system complications. Neuromodulation applications are used reliably in the urological treatment of MS patients. The aim of this study was to compare the efficacy of different neuromodulation techniques, transcutaneous posterior tibial nerve stimulation and repetitive transcranial magnetic stimulation, in patients with MS reporting lower urinary tract symptoms.

NCT ID: NCT04815226 Enrolling by invitation - Clinical trials for Urinary Incontinence

The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.

NCT ID: NCT03456089 Enrolling by invitation - Clinical trials for Urinary Bladder, Neurogenic

Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing

Start date: April 15, 2018
Phase: N/A
Study type: Interventional

The investigators have developed a novel pressure monitoring device that hooks to standard urinary catheters. The investigators will be testing how the pressure measurements recorded with this device compare to the gold standard measurement of urodynamics.

NCT ID: NCT03336424 Enrolling by invitation - Multiple Sclerosis Clinical Trials

Urinary Disorders in Patients With Multiple Sclerosis: Invasive Vs Non-invasive Investigations.

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The objective of the study is to describe the current status of MS patients with urinary disorders in Lebanon, and to demonstrate whether invasive investigations improve the management of these patients compared to an optimal non-invasive approach.